Cardiopulmonary Complication in Aneurysmal Subarachnoid Haemorrhage Patients
Ključne riječi
Sažetak
Opis
Laboratory markers daily: Routine laboratory test (blood gases, haemoglobin, thrombocytes, leukocytes, INR, bilirubin, creatinine, c-reactive protein, CK, CK-MB, Tnt, BNP, sodium, potassium, magnesium) are taken at 8 a.m. Study laboratory tests (sensitive ischemia markers, remodelling marker MMP-9 and CgA as surrogate marker for increased sympathetic activity) are taken four times during study period at the same time as cardiac ECHOes and Holtering. Gene sample is taken once on day one.
Primary outcome measurement is to document the incidence of myocardial dysfunction and the predictive factors during the hospital stay and at three months.
Secondary outcome is to assess the impact of cardiac problems on morbidity and mortality during first three months.
Datumi
| Posljednja provjera: | 02/28/2018 |
| Prvo podneseno: | 08/18/2012 |
| Predviđena prijava predata: | 08/20/2012 |
| Prvo objavljeno: | 08/21/2012 |
| Zadnje ažuriranje poslato: | 03/13/2018 |
| Posljednje ažuriranje objavljeno: | 03/14/2018 |
| Stvarni datum početka studija: | 01/31/2012 |
| Procijenjeni datum primarnog završetka: | 07/31/2017 |
| Predviđeni datum završetka studije: | 07/31/2017 |
Stanje ili bolest
Faza
Grupe ruku
| Arm | Intervencija / liječenje |
|---|---|
| subarachnoid haemorrhage nontraumatic subarachnoid haemorrhage |
Kriteriji prihvatljivosti
| Uzrast podoban za studiranje | 18 Years To 18 Years |
| Polovi podobni za studiranje | All |
| Metoda uzorkovanja | Non-Probability Sample |
| Prihvaća zdrave volontere | Da |
| Kriterijumi | Inclusion Criteria: - Patients with nontraumatic subarachnoid haemorrhage - Age > 18 years - Aneurysmal bleeding Exclusion Criteria: - No consent - Age < 18 years - Anticipated brain death < 24 hours - Otherwise moribund patient |
Ishod
Primarne mjere ishoda
1. Incidence of cardiac failure and the impact of cardiac problems on morbidity [6 months]
