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Sphenoid Nasalization in Allergic Fungal Sphenoidal Sinusitis

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Assiut University

Ključne riječi

Sažetak

To study the outcome of different two endoscopic sphenoid procedure for management of allergic fungal sphenoidal sinusitis : sphenoidotomy versus sphenoid nasalization with posterior septectomy .

Opis

Fungal rhinosinusitis classified into invasive and noninvasive subtypes. Phenotypes of noninvasive fungal rhinosinusitis occur in immunocompetent subjects and include: local fungal colonization, fungal ball, and allergic fungal rhinosinusitis. Subtypes of invasive fungal rhinosinusitis include acute invasive fungal rhinosinusitis, chronic invasive fungal rhinosinusitis and granulomatous invasive rhinosinusitis.

The estimated incidence of sphenoid sinusitis is only 2.7% of all nasal sinus infections, also the diagnosis of sphenoid sinus fungal infection is sometimes difficult. Clinical signs are often non specific and nasal endoscopy can be strictly normal.Early diagnosis is therefore difficult and diagnosis is often delayed with headache that may sometimes persists for several years before diagnosis of the disease.

In most cases of sphenoid sinusitis, enlargement of the obstructed sinus ostium is sufficient to provide drainage of retained secretions and reestablish mucociliary clearance.According to Simmen and Jones, a type I sphenoidotomy entails identification of the ostium without further intervention; a type II sphenoidotomy entails enlargement of the ostium upward to the level of the cranial base, and inferiorly to one-half of the sinus height; and a type III sphenoidotomy involves widening the ostium to its most lateral extent.

Eloy et al in 2017 stuited that,In more extensive sphenoid sinus surgery is reserved for cases where in the disease process is extensive or previous surgery has failed. In some cases sphenoid nasalization in which bilateral extended sphenoidotomy is necessary. In this procedure, the posterior aspect of the nasal septum is resected, along with the sphenoid rostrum, the intersinus septum, and other intrasphenoid partitions, creating a common cavity with a broad drainage pathway . It also allows access to the lateral recesses of this sinus.

Datumi

Posljednja provjera: 02/28/2019
Prvo podneseno: 03/16/2019
Predviđena prijava predata: 03/16/2019
Prvo objavljeno: 03/18/2019
Zadnje ažuriranje poslato: 03/16/2019
Posljednje ažuriranje objavljeno: 03/18/2019
Stvarni datum početka studija: 03/31/2019
Procijenjeni datum primarnog završetka: 03/31/2022
Predviđeni datum završetka studije: 09/30/2022

Stanje ili bolest

Fungal Sinusitis

Intervencija / liječenje

Procedure: sphenoidotomy versus sphenoid nasalisation

Faza

-

Grupe ruku

ArmIntervencija / liječenje
Active Comparator: sphenoidotomy (group A)
sphenoidotomy opening of sphenoid sinus ostum and cleaning of the sinus
Active Comparator: sphenoid nasalization (group B)
sphenoid nasalization in which bilateral extended sphenoidotomy, the posterior aspect of the nasal septum is resected, along with the sphenoid rostrum, the intersinus septum, and other intrasphenoid partitions, creating a common cavity with a broad drainage pathway .

Kriteriji prihvatljivosti

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Kriterijumi

Inclusion Criteria:

- Any age.

- Any case of allergic fungal sinusitis unilateral or bilateral involving the sphenoid sinus

Exclusion Criteria:

- Acute invasive fungal sinusitis.

- Previous Sinonasal surgery.

- Unfit patient for surgery.

Ishod

Primarne mjere ishoda

1. rate of recurrence [6 month]

To assess the effect of nasalization of sphenoid sinus on recurrence rate of allergic fungal sinusitis Recurrence will be evaluated by clinical endoscopic evaluationof regular endoscopic examination first visit after one week,the second after 3 weeks and after 3month. CT nose and paranasal sinus will be done after 3 and 6 months.

Sekundarne mjere ishoda

1. Type of caustive organism [2weeks]

microbiological evaluation of the fungal mud will taken for culture to determine the type of the causative organism and determine if the fungal sinusitis is of invasive or non invasive type

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