Study of Obesity Control by Astragalus and Notoginseng Extrats
Ključne riječi
Sažetak
Opis
Obesity refers to the body due to physiological or biochemical function of the change caused by excessive accumulation of body fat, resulting in weight gain. Hence, the aim of this study was to evaluate the effects of the Astragalus and Notoginseng extrats on obesity control by a randomized double-blind and crossover human trial. Subjects with simple obesity (body mass index (BMI) ≥ 27 or body fat ≥ 30%) ingested 5 extrats (n = 19) capsules or placebo (n = 19) perday for 12 weeks of a stage. Anthropometric measurements (body weight, body fat, blood pressure) and blood biochemical markers including fasting blood glucose (FBG), albumin, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, creatinine (Cr), blood urea nitrogen (BUN), AST, ALT were examined every six weeks.
Datumi
| Posljednja provjera: | 11/30/2019 |
| Prvo podneseno: | 08/28/2018 |
| Predviđena prijava predata: | 08/28/2018 |
| Prvo objavljeno: | 08/30/2018 |
| Zadnje ažuriranje poslato: | 12/12/2019 |
| Posljednje ažuriranje objavljeno: | 12/15/2019 |
| Stvarni datum početka studija: | 09/30/2016 |
| Procijenjeni datum primarnog završetka: | 07/31/2017 |
| Predviđeni datum završetka studije: | 09/30/2017 |
Stanje ili bolest
Intervencija / liječenje
Dietary Supplement: InnoSlim
Dietary Supplement: Placebo
Faza
Grupe ruku
| Arm | Intervencija / liječenje |
|---|---|
| Active Comparator: InnoSlim Subjects ingested 2 capsules InnoSlim® (Experimental group) in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. | Dietary Supplement: InnoSlim Subjects ingested 2 capsules (Experimental group) in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. Anthropometric measurements such as body weight, body fat, waistline, hipline, blood pressure (systolic blood pressure [SBP] and diastolic blood pressure [DBP]) and blood biochemical parameters including FBG, albumin, TC, TG, HDL-C, LDL-C, Cr, BUN, AST and ALT were measured every six weeks. |
| Placebo Comparator: Placebo Subjects ingested 2 capsules placebo (Control group) in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. | Dietary Supplement: Placebo Subjects ingested 2 capsules placebo in the morning and 3 capsules in the evening (5 capsules/d) for 12 weeks of a stage. Anthropometric measurements such as body weight, body fat, waistline, hipline, blood pressure (systolic blood pressure [SBP] and diastolic blood pressure [DBP]) and blood biochemical parameters including FBG, albumin, TC, TG, HDL-C, LDL-C, Cr, BUN, AST and ALT were measured every six weeks. |
Kriteriji prihvatljivosti
| Uzrast podoban za studiranje | 20 Years To 20 Years |
| Polovi podobni za studiranje | All |
| Prihvaća zdrave volontere | Da |
| Kriterijumi | Inclusion Criteria: - Body mass index (BMI) ≥ 27 or body fat ≥ 30%; - No history of serious diseases associated with heart, liver, kidney, endocrine systems or other organs; - No drugs consumption. Exclusion Criteria: - BMI >35; - Alcoholic; - US-controlled diabetics; - Stoke in past one year; - High blood pressure; - Mental diseases or melancholia; - Pregency or breast-feeding a child. |
Ishod
Primarne mjere ishoda
1. The changes of body weight and BMI of the subjects. [12 weeks]
Sekundarne mjere ishoda
1. The changes of triglyceride (TG) of the subjects [12 weeks]
