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3 rezultati
Identification of NF-κB inhibitors following Shenfu injection and bioactivity-integrated UPLC/Q-TOF-MS and screening for related anti-inflammatory targets in vitro and in silico.
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BACKGROUND
Shenfu injection (SFI) is a commercial medicinal product approved by the China Food and Drug Administration that is widely used in the treatment of stroke and coronary heart disease. However, the material basis and the mechanism of SFI are not fully understood.
OBJECTIVE
With network
pH-Zone-Refining Counter-current Chromatography for Two New Lipo-alkaloids Separated from Refined Alkaline Extraction of Kusnezoff monkshood root.
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An efficient and refined method for the separation of six aconitine-type alkaloids from the alkaline prepared "Kusnezoff monkshood root" was extablished. It is the first study that two new lipo-alkaloids were successfully isolated from refined sample by pH-zone-refining counter-current
[Quality consistency evaluation of Fuzi formula granules using determination of multi-component contents by HPLC-MS/MS method].
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To establish HPLC-MS/MS method for simultaneous determination of 14 toxic or active components in Fuzi formula granules, and further analyze the quality consistency of 29 batches of formula granules by considering the cluster analysis (CA), principal component analysis (PCA), and partial least
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