acromegaly/edema

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Rapidly reversible myocardial edema in patients with acromegaly: assessment with ultrafast T2 mapping in a single-breath-hold MRI sequence.

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OBJECTIVE The purpose of this study was to use a single-breath-hold T2-mapping MRI sequence to evaluate the reversibility of myocardial edema in patients treated for acromegaly. METHODS Before and after treatment, 15 patients with acromegaly underwent myocardial T2 mapping with an experimental

[A 65-year-old patient with acromegaly, recent appearance of dyspnea and tibial edema].

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Subclinical carpal tunnel syndrome in acromegaly.

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Median nerve conduction was studied in 16 acromegalic patients with asymptomatic carpal tunnel syndrome (CTS) to examine the incidence of subclinical CTS. Thirteen patients (81%) and 23 hands (72%) demonstrated subclinical CTS, 10 bilaterally and three unilaterally in the dominant hand. The

Dermatologic manifestations of acromegaly: A case in point and a focused review.

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Acromegaly is a systemic syndrome caused by overproduction of growth hormone. Cutaneous, endocrine, cardiovascular, skeletal, and respiratory systems are affected. Cutaneous changes in acromegaly relate to overexpression of growth hormone and insulin-like growth factor 1 on skin cells and adnexa.

Skin manifestations in acromegaly.

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Cutaneous changes in acromegaly result from excess GH and IGF-1 action on skin cells and adnexae. Skin puffiness due to dermal glycosaminoglycan accumulation and edema are most prominent in the face, hands and feet. Oily skin with large pores, hypertrichosis, and excessive sweating are common

Magnetic resonance imaging findings in 15 acromegalic cats.

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Feline acromegaly is characterized by chronic excessive growth hormone secretion, most commonly caused by a functional pituitary adenoma. In this study, acromegaly was diagnosed in 15 cats on the basis of compatible clinical signs, laboratory, and magnetic resonance imaging (MRI) findings. MRI

Does the physiological acromegaly of pregnancy benefit the fetus?

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Pregnancy is accompanied by notable changes in the secretion of growth hormone (GH) and the insulin-like growth factors (IGFs). A GH variant produced by the placenta is discernible in maternal plasma from early pregnancy, rising exponentially until 37 weeks. Meanwhile, pituitary GH gradually drops

Voice Characteristics in Patients with Acromegaly during Treatment.

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Active acromegaly is characterized by Growth Hormone and Insulin-like Growth Factor (IGF)-1 excess. Voice complaints are common in active acromegaly and are suggested to be caused by effects of Growth Hormone or IGF-1 on vocal cords and the surrounding soft tissues. Prospective studies

Acromegaly presenting as cardiac failure.

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BACKGROUND In acromegaly, specific structural and functional changes in the heart appear to contribute to the increased mortality in this disease. This disease is uncommon in Nigeria, West Africa and little has been published about it; also rare is clinically evident heart failure. We are therefore

Prevalence and pathogenesis of sleep apnea and lung disease in acromegaly.

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Respiratory disorders are common and important complications in acromegaly. Patients suffering from acromegaly display a 1.6-3.3 fold increase in mortality rate, which is due to respiratory disorders in 25% of cases. In these patients, mortality for lung disease is 2-3 fold higher than in the

Acromegaly with cardiomyopathy, cardiac thrombus and hemorrhagic cerebral infarct: a case report of therapeutic dilemma with review of literature.

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BACKGROUND Cardiomyopathy with congestive heart failure (CHF) is a rare complication of growth hormone (GH)-secreting pituitary adenoma occurring in 3% of cases. We report a case of acromegaly complicated not only by CHF but also by the presence of intracardiac thrombus and cardioembolic stroke with

A case of juvenile acromegaly that was initially diagnosed as severe congestive heart failure from acromegaly-induced dilated cardiomyopathy.

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Acromegaly is characterized by chronic hypersecretion of growth hormone (GH) and is associated with increased mortality rate because of the potential complications such as cardiovascular disease, respiratory disease, or malignancy, which are probably caused by the long-term exposure of tissues to

Negative-pressure pulmonary edema after transsphenoidal hypophysectomy. Case report.

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OBJECTIVE Negative-pressure pulmonary edema (NPPE) is a rare complication that evolves rapidly after acute or chronic obstruction of the airways. The objective of this report was to present a case of NPPE after upper airways obstruction in a patient with acromegaly who underwent transsphenoidal

Fixity of vocal cords and laryngocele in acromegaly.

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Acromegalic patients have a reduced life expectancy mainly due to cardio-, cerebrovascular and respiratory disorders and increased prevalence of neoplasias. Particularly, the pathogenesis of respiratory disorders in acromegalics is debated. Laryngeal abnormalities are not yet well clarified even if

Acromegaly accompanied by Turner syndrome with 47,XXX/45,X/46,XX mosaicism.

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A 33-year-old woman was hospitalized for examination of edematous laryngopharynx. She was acromegalic. A pituitary adenoma with elevated serum levels of growth hormone (GH) and insulin-like growth factor-I (IGF-I) was detected, indicating acromegaly caused by GH-secreting pituitary adenoma. Multiple

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