antiandrogens/sarkom

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[Steroid hormone receptors in osteogenic sarcomas].

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The method of hormone-receptor complex precipitation with protamine sulfate was used in 57 males suffering osteogenic sarcoma to identify and evaluate cytoplasmic androgen (AR) and estrogen receptor (ER) levels versus age and prior treatment as well as to assess their prognostic significance. AR

[Androgen receptors in the cytosol fraction of a spontaneous osteogenic sarcoma in dogs].

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The paper discusses results of the assay of androgen receptors in the cytosol fraction of osteogenic sarcoma (primary tumor and metastases) in 17 dogs. In some cases, osteogenic sarcoma and its metastases revealed androgen receptors in a wide range of concentrations (15-340 fmol/mg protein).

Alveolar soft part sarcoma mimics prostate cancer metastasis.

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A 61-year-old man presented to the oncology clinic with Gleason 9 (4 + 5) prostate cancer. Staging CT showed multiple nodules in both lungs. Since the lung lesions were too small for biopsy, he was started on anti-androgen therapy for suspected metastatic, hormone-sensitive prostate cancer. While

Paraneoplastic Scleroderma: Are There Any Clues?

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Dear Editor, Scleroderma associated with neoplasia is rare, with only a small number of cases reported. We describe 4 patients with paraneoplastic scleroderma who were treated at the I. Department of Dermatovenereology, St. Anna Hospital, during the period between 2004 and 2014. The patients were

Eight pillars of oncorheumatology: Crossroads between malignancies and musculoskeletal diseases

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RELATIONSHIP BETWEEN MALIGNANCIES AND MUSCULOSKELETAL DISEASES: Oncorheumatology is the meeting point of tumor formation and rheumatic musculoskeletal diseases (RMD). Multiple interactions exist between these two medical specialties. One major field is the topic of malignancies associated with

Prophylactic breast bud radiotherapy for patients taking bicalutamide: should this still be practised for patients with prostate cancer?

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Prophylactic breast bud radiotherapy is used to prevent gynaecomastia and mastalgia in patients with prostate cancer who are being treated with antiandrogen and oestrogen therapy. Here a case is presented of a patient who developed soft-tissue sarcoma of the breast subsequent to breast bud

Metabolic treatment of cancer: intermediate results of a prospective case series.

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BACKGROUND The combination of hydroxycitrate and lipoic acid has been demonstrated by several laboratories to be effective in reducing murine cancer growth. METHODS All patients had failed standard chemotherapy and were offered only palliative care by their referring oncologist. Karnofsky status was

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