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The present investigation was performed to assess the concentrations of four heavy metals-lead (Pb), cadmium (Cd), copper (Cu), and cobalt (Co)-in goats reared in the vicinity of an industrial area of West Bengal, India, including soil, water, and feedstuffs; tissues of liver, kidney, lung, spleen,
Lassa fever is widespread in West Africa, where the case fatality is about 16% in hospitalized adult patients. The clinical course is highly variable, with a few patients developing severe disease with bleeding, adult respiratory distress syndrome, encephalopathy and hypovolemic shock. We studied 70
OBJECTIVE
To study the effect of daily treatment with 50 mg of aspirin (ASA) on the hypertensive pregnancy complications and on the production prostacyclin (PGI2) and thromboxane A2 (TxA2) in high risk pregnant women and their infants.
METHODS
Placebo controlled prospective
The clinical signs and lesions of Nubian goats and Desert sheep orally dosed with fresh and dry leaves and stems of Ipomoea carnea at 2.5, 5 and 10 g/kg/day were studied. The signs of Ipomoea poisoning were inappetence, depression, weakness of the hind limbs, dyspnea, staggering, and pallor of the
OBJECTIVE
During anticoagulant therapy, major bleeding is one of the most severe adverse effects. This study aimed to evaluate the relationships between ABCB1, ABCG2, and CYP3A5 polymorphisms and plasma trough concentrations of apixaban, a direct inhibitor of coagulation factor X.
METHODS
A total of
Urinary trypsin inhibitor (UTI), a serine protease inhibitor, has been widely used for patients with inflammatory disorders including disseminated intravascular coagulation, shock, and pancreatitis in Japan. Our recent studies using UTI-null (-/-) mice have shown that UTI protects against systemic
Any work on red blood cells requires information about the characteristics of a cell population. Using buoyant density separation of red blood cells (RBC) in a dextran medium during a bleeding anemia of rabbits cell-physiological, ribosomal, mitochondrial and cytoplasmic criteria were estimated in
OBJECTIVE
To study the influence of high-voltage electric burn on the microcirculation of heart in rabbit.
METHODS
One-hundred and twenty New Zealand rabbits of clean grade were divided into control group (C) and electric burn group (EB) according to the random number table, with 60 rabbits in each
Cylindrospermopsin (CYN) is a tricyclic alkaloid toxin produced by fresh water cyanobacterial species worldwide. CYN has been responsible for both livestock and human poisoning after oral exposure. This study investigated the toxicity of CYN to pregnant mice exposed during different segments of
Drug-related hepatotoxicity is now the leading cause of acute liver failure in the United States, especially among patients who have no prior liver disease. Nicardipine is the only IV calcium channel blocker available for the short-term treatment of hypertension with a considerably good safety
The study evaluated the damage caused by Haemonchus contortus in terms of blood loss, faecal clearance of plasma protein and elevated serum enzyme activity in Sahabadi sheep. Apparently healthy Sahabadi sheep (n = 15) were selected randomly based on phenotypic characteristics and divided into two
Haematological and serum biochemical examinations were carried out on 12 high grade bull calves fed Gnidia latifolia (Meisn). This resulted in lymphocytopaenia, increased blood urea nitrogen and lactate dehydrogenase. There were no changes in the red blood cell counts, neutrophil counts, aspartate
OBJECTIVE
Determine whether inflow occlusion is correlated with peak-postoperative serum-transaminases (PSTs) and whether PST is predictive of outcome after liver resections.
BACKGROUND
PST is used as the surrogate of ischemia reperfusion and as the main endpoint in prospective trials of inflow
The feasibility of transcatheter arterial chemo-embolization (TACE) combined with intratumoral injection of cisplatin as treatment for hepatocellular carcinoma. 30 cases receiving TACE were denoted the TACE group, another 30 cases receiving TACE combined with an intratumoral multi-point injection of
OBJECTIVE
To investigate acute toxicity of microcystin-LR in BALB/c mice.
METHODS
BALB/c mice were subjected to intraperitoneal injection of microcystin-LR at the half lethal dose (LD50) and 1/2 LD50, and the organ weight indices and various biochemical indices were determined 30 min and 4 h after