The experimental intervention is the installation of a dynamic LED-light system in 10 separate patient single rooms. The system includes three elements: a window jamb built-in light panel, two ceiling mounted lamps, and a wall mounted lamp. All lamps will have a dynamic, time dependent frequency distribution and intensity of light.

The usual care is constant standard LED-light with two elements: two ceiling mounted lamps and a wall mounted lamp.

Major Depressive Disorder

Dynamic Light

Usual care

Psychiatic Hospital Copenhagen

ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients

Dynamic LED-light Versus Usual Care for Depressed Inpatient: A Randomised Clinical Trial

A scale, consisting of 7 items from the Hamilton depression Rating Scale, measuring severity of depression. Total scores from zero (no depression) to 24 (most severe depression)

Suicidal Ideation Attributes Scale (SIDAS). A scale measuring suicidal ideation. Total scores from zero (no suicidal ideation) to 50 (highest level of suicidal ideation).

A Scale, consisting of 17 items of the Hamilton Depression Rating Scale, measuring severity of depression. Total scores from zero (no depression) to 52 (most severe depression)

Quality of life scale with four domains. Each scores is transformed to a zero (lowest quality of life) to 100 (highest quality of life) score.

We will make data from this study available on reasonable request once the results are published

Mental Health Centre Copenhagen

Mental Health Services in the Capital Region, Denmark

Toyota-Fonden

Grosserer L. F. Foghts Fond Denmark

ELFORSK Danish Energy

Technical University of Denmark

Blinding of depression severity assessment

Powdered berry extract containing 500mg of polyphenols

Berryfruit juice containing 500mg polyphenols

Healthy

Berry Polyphenols

Placebo control containing sugar and artificial flavouring.

Placebo

The New Zealand Institute for Plant & Food Research Ltd

The Effect Of Berry Polyphenols On Human Behaviour

A Double Blind, Placebo Controlled Study Measuring The Effect Of Berry Polyphenols On Mood And Cognition In Healthy Adults

Attention and vigilance will be measured at baseline ad then 1 hour post supplementation of the study treatment. at baseline the digit vigilance task, stroop task and RVIP task will be completed. One hour post supplementation of the study treatment, 7 sets of digit vigilance, stroop and RVIP will be completed. The outcome measures will be treated as change from baseline scores.

asthenopia/serotonin

ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients

The Effect Of Berry Polyphenols On Human Behaviour

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