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benzopyrone/mučnina

Veza se sprema u međuspremnik
ČlanciKliničkim ispitivanjimaPatenti
3 rezultati

Phase II evaluation of coumarin (1,2-benzopyrone) in metastatic prostatic carcinoma.

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The unavailability of effective treatment of metastatic hormone refractory prostatic carcinoma warrants trials of new and promising treatments. Coumarin is an investigational new drug that has produced objective tumor regression in some patients with metastatic renal cell carcinoma and malignant

Phase I evaluation of coumarin (1,2-benzopyrone) and cimetidine in patients with advanced malignancies.

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Fifty-four patients with advanced malignancies were treated on this phase I trial of coumarin and cimetidine. The dose of coumarin was escalated, with three patients treated at each dose level, while the cimetidine dose was held constant at 300 mg four times daily. Patients received coumarin alone

Treatment of lymphedema of the arms and legs with 5,6-benzo-[alpha]-pyrone.

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BACKGROUND Benzopyrones can reduce the volume of high-protein edema fluid by stimulating proteolysis. These compounds provide a method for removing excess protein and its consequent edema and reduce its clinical sequelae, such as chronic inflammation and secondary infections. METHODS We conducted a
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