betula chichibuensis/protuupalno

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Anti-inflammatory and anti-nociceptive effect of Betula platyphylla var. japonica in human interleukin-1β-stimulated fibroblast-like synoviocytes and in experimental animal models.

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BACKGROUND Traditional medicine has widely been used Betula platyphylla var. japonica to treat various inflammatory diseases including arthritis. OBJECTIVE To determine the anti-inflammatory, anti-nociceptive, and anti-arthritic effects of Betula platyphylla in interleukin-1β (IL-1β)-stimulated

Studies on the antiinflammatory activity of Betula alnoides bark.

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The antiinflammatory activity of Betula alnoides extract was evaluated in acute and subacute inflammation models. The extract was also evaluated for antiinflammatory activity in sheep RBC induced sensitivity and in membrane stabilization models. Except for the sheep RBC induced sensitivity model,

Evaluation of Anti-HIV-1 Integrase and Anti-Inflammatory Activities of Compounds from Betula alnoides Buch-Ham.

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Betula alnoides is a medicinal plant in Thai traditional longevity preparations. The crude extracts of this plant possess various biological activities. However, the isolated compounds from this plant have no reports of anti-HIV-1 integrase (IN) activity. Therefore, the present study aims to

The Griess assay: suitable for a bio-guided fractionation of anti-inflammatory plant extracts?

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In the field of inflammation research the inducible nitric oxide synthase (iNOS) became an important pharmacological target, since overproduction of nitric oxide (NO) after induction of this enzyme seems to be associated with numerous pathological conditions. NO released from cells can be detected

Inhibition of corneal inflammation following keratoplasty by birch leaf extract.

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The objective of this study was to determine the effect of birch leaf (Betula pendula) extract (BPE) on corneal inflammation following keratoplasty in the rat model. T cells were stimulated in vitro in the presence of BPE. Proliferation, activation phenotype and the number of apoptotic/necrotic

Quality evaluation of different preparations of dry extracts of birch (Betula pendula Roth) leaves.

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Qualitatively prepared dry extracts are advantaged over conventional fluid extracts. Extracts of Betula pendula Roth leaves possess mild diuretic effects and anti-inflammatory activity. In this work, the spray-drying and lyophilisation processes were evaluated for producing dry extracts of birch

Betula platyphylla attenuated mast cell-mediated allergic inflammation in vivo and in vitro.

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OBJECTIVE Betula platyphylla (B. platyphylla) has traditionally been used in Korea to treat inflammatory diseases. However, the exact mechanism that accounts for the anti-inflammatory effect of B. platyphylla is not completely understood. The aim of the present study is to elucidate whether and how

Identification and isolation of pharmacologically active triterpenes in Betuale cortex, Betula pendula Roth., Betulaceae.

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Betulae cortex, Betula pendula Roth., Betulaceae, comprise triterpene substances which are confirmed to posses very important pharmacological activities such as anti-inflammatory, anticancer and antiviral. In this study, extraction of triterpene substances from both, inner and external birch bark

Study of the betulin enriched birch bark extracts effects on human carcinoma cells and ear inflammation.

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BACKGROUND Pentacyclic triterpenes, mainly betulin and betulinic acid, are valuable anticancer agents found in the bark of birch tree. This study evaluates birch bark extracts for the active principles composition. RESULTS New improved extraction methods were applied on the bark of Betula pendula in

Phenolic constituents from the twigs of Betula schmidtii collected in Goesan, Korea.

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Six undescribed phenolic derivatives along with thirty two known compounds were isolated from the twigs of Betula schmidtii. The chemical structures were characterized through extensive spectroscopic analysis and chemical methods. All known compounds were first isolated in this plant. The

Cytotoxicity of white birch bud extracts: Perspectives for therapy of tumours.

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Birch buds (Gemmae Betulae) are widely used in Russian and Chinese traditional medicine mainly as a diuretic and diaphoretic agent but also as an antiseptic, anti-inflammatory and analgesic. Despite the long history of therapeutic use of birch buds in folk medicine, the existing information on their

Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders

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Background: Acacetin is a di-hydroxy and mono-methoxy flavone present in various plants, including black locust, Damiana, Silver birch. Literature information revealed that acacetin exhibits an array of pharmacological potential including

IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis.

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BACKGROUND Seasonal allergic rhinitis is a chronic inflammation in the nasal mucosa triggered by inhaled aeroallergens. The inflammatory reaction is controlled by allergen-specific T cells, but where and how these T cells become activated is not fully understood. OBJECTIVE We wanted to determine

Bioactive triterpenoids from twigs of Betula schmidtii.

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Investigation of the MeOH extract of Betula schmidtii twigs resulted in the isolation and identification of three new triterpenoids (1-3), along with ten known ones (4-13). The structures of new compounds (1-3) were elucidated by spectroscopic methods, including 1D, 2D NMR (1H and 13C NMR, COSY,

Medicinal plants of the genus Betula--traditional uses and a phytochemical-pharmacological review.

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BACKGROUND Trees and shrubs of the genus Betula (Betulaceae) inhabit various ecosystems in temperate and boreal climate zones of the northern hemisphere. The healing properties of Betula bark and bark extracts have been known for a long time in traditional medicine in different parts of the world.

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