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boldine/seizures

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ČlanciKliničkim ispitivanjimaPatenti
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Acute Boldine Treatment Induces Anti-convulsant Effects in Mice through its Antioxidant Activity.

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Boldine is a natural antioxidant that exhibits some important pharmacological properties, which is due to its free radical scavenging effects. And at the same time, reactive oxygen species (ROS) has an important role in pathogenesis of seizure; hence, reducing it via antioxidants like boldine seems

Sub-chronic boldine treatment exerts anticonvulsant effects in mice.

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OBJECTIVE Boldine is an aporphine alkaloid which is best known for its antioxidant, anti-inflammatory and cytoprotective characteristics. It seems that all these activities are related to boldine ability to scavenge reactive free radicals. As indicated by several pieces of evidence, free radicals
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