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calcicola/rak

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Cytotoxic sesquiterpene lactones from Saussurea calcicola.

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Seven sesquiterpene lactones were isolated by the chromatographic separation of the MeOH extract of the aerial parts of Saussurea calcicola (Compositae). Their structures were determined spectroscopically to be cynaropicrin (1), arguerin B (2), cebellin F (3), 8alpha-hydroxy-11alpha,

Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola.

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As part of an ongoing program to identify new bioactive compounds from Irish marine bioresources, we selected the subtidal sponge Spongosorites calcicola for chemical study, as fractions of this species displayed interesting cytotoxic bioactivities and chemical profiles. The first chemical

Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.

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A bioassay-guided fractionation of the EtOH extract of the Madagascan plant Terminalia calcicola led to the isolation of two new cytotoxic xanthones, termicalcicolanone A (1) and termicalcicolanone B (2). The structures of the new compounds were established on the basis of one- and two-dimensional

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest.

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Bioassay-guided fractionation of the ethanol extract obtained from the fruits of Rheedia calcicola led to the isolation of two new guttiferone analogues, guttiferones K (1) and L (16-hydroxyguttiferone K) (2). The structures of 1 and 2 were established on the basis of extensive interpretation of
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