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camptotheca/antivirusno

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ČlanciKliničkim ispitivanjimaPatenti
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Molecular characterization of two anthranilate synthase alpha subunit genes in Camptotheca acuminata.

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The potent anticancer and antiviral compound camptothecin (CPT) is a monoterpene indole alkaloid produced by Camptotheca acuminata. In order to investigate the biosynthetic pathway of CPT, we studied the early indole pathway, a junction between primary and secondary metabolism, which generates

Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata.

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Leaf spots and root rots are major fungal diseases in Camptotheca acuminata that limit cultivation of the plant for camptothecin (CPT), a promising anticancer and antiviral alkaloid. Bioassays showed that pure CPT and flavonoids (trifolin and hyperoside) isolated from Camptotheca effectively control

Camptothecin and 10-hydroxycamptothecin from Camptotheca acuminata hairy roots.

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Camptothecin (CPT) is an anticancer and antiviral alkaloid produced by the Chinese tree Camptotheca acuminata (Nyssaceae) and some other species belonging to the families Apocynaceae, Olacaceae, and Rubiaceae. Bark and seeds are currently used as sources for the drug. Several attempts have been made

Medicinal plants: a public resource for metabolomics and hypothesis development.

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Specialized compounds from photosynthetic organisms serve as rich resources for drug development. From aspirin to atropine, plant-derived natural products have had a profound impact on human health. Technological advances provide new opportunities to access these natural products in a metabolic
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