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camptotheca/nekroza

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ČlanciKliničkim ispitivanjimaPatenti
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Camptothecin fails to induce apoptosis in tumor necrosis factor-alpha-treated HaCaT cells.

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Camptothecin (CPT), a DNA topoisomerase I inhibitor, was originally isolated from the fruits of the Chinese Camptotheca acuminata tree. CPT and its derivatives have been used in the treatment of psoriasis and cancer in China for decades. It is well known that tumor necrosis factor-α (TNF-α) is a key

In silico database screening of potential targets and pathways of compounds contained in plants used for psoriasis vulgaris.

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Reviews and meta-analyses of clinical trials identified plants used as traditional medicines (TMs) that show promise for psoriasis. These include Rehmannia glutinosa, Camptotheca acuminata, Indigo naturalis and Salvia miltiorrhiza. Compounds contained in these TMs have shown activities of relevance
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