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camptotheca/sarkom
Veza se sprema u međuspremnik
2 rezultati
[Topotecan for pediatric patients with resistant and recurrent solid tumors].
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BACKGROUND
Topotecan is a cytotoxic drug isolated from the Camptotheca acuminata tree (from China). It is able to block the enzyme DNA topoisomerase I and has recently been used in the treatment of pediatric cancer.
OBJECTIVE
To evaluate our preliminary experience with topotecan in the second line
Camptothecin and taxol: historic achievements in natural products research.
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The research team of Dr. Monroe E. Wall and Dr. Mansukh C. Wani of Research Triangle Institute discovered two first-in-class life-saving chemotherapeutic agents. Camptothecin, first isolated and identified from Camptotheca acuminata, was found to kill cancer cells uniquely via topoisomerase I
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