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Epigenetic Tools as Prognostic Predictors in Covid19

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The objectives of this observational study are 1) To investigate why COVID-19 infection causes different biological behavioral patterns in individuals, 2) To determine the role of epigenetic mechanisms here to detect the difference between individuals, 3)To determine the effectiveness of this

Clinical Trial of Efficacy and Safety of ММН-407 in the Treatment of Influenza in Outpatient Adults

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Design: a multicenter, placebo-controlled, double-blind, randomized clinical trial in parallel groups. The study will include both male and female patients aged 18-64 years with clinical signs of influenza within the first 24 hours of the onset of illness. The influenza diagnosis must be supported

LMN-101 in a Campylobacter Human Challenge Model

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Healthy subjects will be randomized within one of the following sequential dose cohorts: - LMN-101, six 500-mg capsules orally three times daily for 28 days (n=21), or identical-appearing placebo (n=7); or - LMN-101, two 500-mg capsules and four 500-mg placebo capsules orally three times daily for

Transcranial Alternating Current Stimulation Treating Post-stroke Depression

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Patients with post-stroke depression (PSD) have more dysfunction, poorer recovery outcomes, and higher morbidity and mortality in the first year after stroke onset than those patients without stroke. Some therapeutic methods have shown to be effective for PSD, including antidepressants, non-drug

Clinical Trial to Investigate CT38 in the Treatment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is a complex disorder that may be triggered by infection or other stressors (e.g., emotional or physical trauma, immune activation, chemical exposures). Its hallmark is a reduced capacity for physical and mental activity manifest as

PEMBRO With Chemo in Neo Adj Treatment of Ovarian Cancer .

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The standard procedure for initial diagnosis recommends the realization of laparoscopy first for all suspicious advanced ovarian carcinoma. This procedure should able to confirm histo-logical diagnosis and to describe the all abdominal extension of the disease. For advanced stages, complete primary

Self-verification and Support Via Mobile Phones Drastically Improves Tuberculosis Treatment Success in LMIC Settings

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Tuberculosis (TB) is the deadliest infectious disease in the world. The latest estimates suggest there were 10.4 million cases in 2015 and 1.8 million TB deaths. Despite the availability of highly effective medications for treating TB in the developing world, lack of adherence to the treatment

A Perspective Study of Cancer-related Fatigue in Gynecologic Cancer Patients Under Chemotherapy

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About 60 gynecologic cancer patients' medical records are expected to collect and analyze in this retrospective study. The data collection from medical records of gynecologic cancer patients who had received chemotherapy with or without prescription drug treatment for cancer-related fatigue include

Feasibility Study of Monitoring by Web-application on Cytopenia Related to Chemotherapy

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The hematological toxicity is frequent and sometimes severe complication of chemotherapy used in onco-hematology. The most frequent is the neutropenia. It is defined by Neutrophils rate lower than 1 Giga/L. The patient can then have a risk of fever or serious infection which requires a

Effect of Adjunctive Misoprostol Treatment on Blood Loss at Vaginal Delivery

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Background Some maternal blood loss normally occurs at the time of vaginal delivery. The best estimates indicate that a loss of approximately 500 mL is average, with a range of about 250-700 mL.[1,2] Some of this bleeding arises from birth canal lacerations or surgical incisions (i.e., episiotomy),

Evaluating the Role of Chloroquine for Malaria Elimination

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This surveillance study is a two-arm prospective evaluation of parasitological responses to directly observed treatment with CQ (vs. placebo) for the clearing of asymptomatic parasitemia. People with asymptomatic P. falciparum parasitaemia, defined as the presence of a P. falciparum infection in the

Aerobic Exercise and Flu-like Symptoms Following Interferon Beta 1a Injections in Patients With Multiple Sclerosis?

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Flu-like symptoms (FLS) such as fever, muscle aches, chills, and fatigue are common side effects of interferon beta (IFN-ß) treatment and may affect the willingness of patients with multiple sclerosis (MS) to initiate therapy. The initiation phase of MS treatment is a critical period that can affect

Banlangen Granules Anti-seasonal Influenza Study

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Inclusion criteria: 1. Patients have confirmed influenza A(H1N1,H3N2) or influenza B virus infection by real time PCR 2. age between 18-65 years old 3. axillary temperature ≥38ºC and with at least two constitutional symptoms (headache, chill, myalgia ,or fatigue) and one respiratory symptom (cough

ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia

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Hematopoietic stem cell transplantation (SCT) is an effective treatment for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). For patients transplanted in first remission or with low risk MDS, approximately 60% of patients have achieved long-term disease free survival. Patients with
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