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Chorioamnionitis

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Chorioamnionitis is an infection that can occur before labor, during labor, or after delivery. It can be acute, subacute, or chronic. Subacute chorioamnionitis is associated with chronic lung disease in the infant. Chronic chorioamnionitis is associated with retinopathy of prematurity, very low

Prevalence and risk factors of chorioamnionitis among adolescents.

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OBJECTIVE To identify the prevalence of chorioaminionitis and unique risk factors for this disorder among adolescents under 18 years of age. METHODS At their first prenatal visit we interviewed 352 adolescents who received prenatal care and delivered an infant at our institution between April 20,

Histologic chorioamnionitis and risk of neurodevelopmental impairment at age 10 years among extremely preterm infants born less than 28 weeks of gestation.

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Children born extremely preterm whose placenta had histologic evidence of chorioamnionitis have early brain dysfunction, but little is known about neurological development at 10 years of age.We investigated the association between histologic

Risk factors for post-operative wound infection in the setting of chorioamnionitis and cesarean delivery.

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OBJECTIVE The objective of this study was to identify factors associated with an increased risk of post-operative wound infection in women with chorioamnionitis who undergo cesarean delivery. METHODS We conducted a retrospective cohort study of women with clinical chorioamnionitis who underwent

Mechanisms of Lung Injury and Bronchopulmonary Dysplasia.

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Although bronchopulmonary dysplasia (BPD) is the most frequent adverse outcome for infants born at < 30 weeks gestational age, there remain major gaps in understanding the pathophysiology, and thus there are few effective targeted therapies to prevent and treat BPD. This review will focus on the

Effects of smoking, alcohol, and drugs of abuse on the outcome of "expectantly" managed cases of preterm premature rupture of membranes.

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We evaluated the outcome of pregnancies complicated by preterm premature rupture of membrane (PROM) in order to determine if tobacco, alcohol, or illicit drug usage were associated with alterations in pregnancy or neonatal outcome. Comparisons in outcome were made with respect to tobacco, alcohol,

Unexpected term NICU admissions: a marker of obstetrical care quality?

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Unexpected admissions of term neonates to the neonatal intensive care unit and unexpected postnatal complications have been proposed as neonatal-focused quality metrics for intrapartum care. Previous studies have noted significant variation in overall hospital neonatal intensive care

Maternal weight gain and neonatal outcomes in women with class III obesity.

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Objective: Obesity in the USA continues to be a prominent medical and public health concern. Due to increasing rates of maternal obesity, the current Institute of Medicine (IOM) guidelines recommend 11-20 pounds of total weight gain during pregnancy in women with a BMI ≥30 kg/m².

Risk factors for acute pulmonary edema in preterm delivery.

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OBJECTIVE To determine the risk factors for pulmonary edema in women with preterm delivery. METHODS This was a case-controlled study of 52 (6.7%) cases with and 722 (93.3%) cases without pulmonary edema in a cohort of women who delivered between 24 and 33 weeks. Univariate and logistic regression

Maternal serum dehydroepiandrosterone sulfate levels and the efficiency of labor in young nulliparas.

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OBJECTIVE To evaluate the maternal serum dehydroepiandrosterone (DHEA) sulfate level as a factor influencing labor "efficiency" at term. METHODS On admission to the labor and delivery unit, blood was collected from 55 term nulliparous women up to 25 years of age in active labor. Following delivery,

Effects of cocaine on the placenta.

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Adverse perinatal outcomes of gravidas using cocaine is well documented, but the effects on the placenta have been difficult to elucidate due to confounding factors such as concurrent use of other drugs. This study compares pathologic findings of 26 placentas from women who used only cocaine during

Prenatal factors and the development of asthma.

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OBJECTIVE There is increasing evidence that both prenatal and perinatal events influence both allergic diseases and early-life respiratory morbidity. RESULTS Studies in the last year have suggested that in-utero exposures including tobacco smoke exposure, dietary exposures including vitamin D, and

Fetal and early postnatal life roots of asthma.

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The origins of asthma might be traced back to events occurring during fetal life. Reduced lung development has been shown to be a risk factor both for viral induced wheeze and allergic asthma. The evidence for a causal relationship between exposure to environmental tobacco smoke, chemical domestic

Pregnancy outcomes among mothers infected with human immunodeficiency virus and uninfected control subjects.

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Between June 26, 1985, and Feb. 24, 1989, 101 seropositive pregnant women and 129 seronegative pregnant women from the same prenatal clinics in Brooklyn and the Bronx were recruited into a prospective study of human immunodeficiency virus infection in pregnant women and their offspring. This report

Use of a focussed teen prenatal clinic at a military teaching hospital: model for improved outcomes of unmarried mothers.

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We evaluated the utility of a focussed, multidisciplinary adolescent clinic in improving perinatal outcomes. The study population included all delivering unmarried teenagers (13-19 years) from January 1, 1993 to December 31, 1995 attending the focussed adolescent obstetrical clinic compared to a

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