chrysosplenetin/laggera

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Chrysosplenetin promotes osteoblastogenesis of bone marrow stromal cells via Wnt/β-catenin pathway and enhances osteogenesis in estrogen deficiency-induced bone loss.

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Chrysosplenetin is an O-methylated flavonol compound isolated from the plant Chamomilla recutita and Laggera pterodonta. The aim of our research is to evaluate the function of Chrysosplenetin on osteogenesis of human-derived bone marrow stromal cells (hBMSCs) and inhibition of estrogen

Inhibition of enterovirus 71 replication by chrysosplenetin and penduletin.

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In recent years, enterovirus 71 (EV71) infections have caused an increasing epidemic in young children, accompanying with more severe nervous system disease and more deaths. Unfortunately, there is no specific medication for it so far. Here we investigated the anti-EV71 activity of chrysosplenetin

[Chemical constituents from Laggera pterodonta].

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OBJECTIVE To study the chemical constituents from Laggera pterodonta. METHODS The compounds were isolated and purified by column chromatographic methods with silica gel, Sephadex LH-20, ODS and preparation HPLC. Their structures were identified by physicochemical properties and spectral

Terpenoids and flavonoids from Laggera pterodonta.

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To study the chemical constituents of aerial parts of Laggera pterodonta (DC.) Benth., the air-dried aerial parts of this plant were powered and extracted with boiling water and purified by silica gel column chromatography and recrystallized. Eleven compounds were obtained from L. pterodonta. They

[Research on antiproliferative effect of flavones isolated from Laggera pterodonta].

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OBJECTIVE To research the cytotoxicity and in vitro antiproliferative effect of the six flavone compounds extracted from Laggera pterodonta. METHODS The cytotoxicity on the normal cells and antiproliferative effect on tumor cells were tested by MTT assay, and then the preliminary structure-activity

[Chemical constituents of Laggera pterodonta].

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OBJECTIVE To study the chemical constituents of Laggera pterodonta. METHODS The ethanol extract of L. pterodonta was isolated by column chromatogramphy on silica gel, ODS, and Sephadex LH-20 to afford compounds. The structures of the obtained compounds were identified by chemical reactions and

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