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cyclopamine/rak
Veza se sprema u međuspremnik
14 rezultati
Use of cyclopamine in the treatment of basal cell carcinoma and other tumors
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BACKGROUND OF THE INVENTION
Basal cell carcinoma (BCC) is a common epithelial tumor. Its incidence increases with increasing age. Current treatments for BCC's include the surgical excision of the tumor together with a margin of normal tissue and, when surgery is not feasible or desirable,
Steroid-derived cyclopamine analogs and methods for using the same in the prevention or treatment of cancer
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BACKGROUND OF THE INVENTION
Breast cancer is the most common cancer among women, other than skin cancer. It is the second leading cause of cancer death in women, after lung cancer. Almost 180,000 women in the United States will be diagnosed with invasive breast cancer in 2007 and over 40,000 women
Steroid-derived cyclopamine analogs and methods for using the same in the prevention or treatment of cancer
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BACKGROUND OF THE INVENTION
Breast cancer is the most common cancer among women, other than skin cancer. It is the second leading cause of cancer death in women, after lung cancer. Almost 180,000 women in the United States will be diagnosed with invasive breast cancer in 2007 and over 40,000 women
Cyclopamine tartrate salt and uses thereof
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to novel methods for the treatment of cancer. More specifically, the present invention relates to the inhibition of the hedgehog signaling pathway by the direct binding of a cyclopamine derivative to protein
Cyclopamine analogues and methods of use thereof
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BACKGROUND OF THE INVENTION
The hedgehog signaling pathway is essential for numerous processes during embryonic development. Members of the hedgehog family of secreted proteins control cell proliferation, differentiation and tissue patterning. The pathway was first deciphered in the fruit fly
Cyclopamine analogues and methods of use thereof
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BACKGROUND OF THE INVENTION
The hedgehog signaling pathway is essential for numerous processes during embryonic development. Members of the hedgehog family of secreted proteins control cell proliferation, differentiation and tissue patterning. The pathway was first deciphered in the fruit fly
Cyclopamine analogues and methods of use thereof
Samo registrirani korisnici mogu prevoditi članke
Prijavite se / prijavite se
BACKGROUND OF THE INVENTION
The hedgehog signaling pathway is essential for numerous processes during embryonic development. Members of the hedgehog family of secreted proteins control cell proliferation, differentiation and tissue patterning. The pathway was first deciphered in the fruit fly
Cyclopamine analogues and methods of use thereof
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Prijavite se / prijavite se
BACKGROUND OF THE INVENTION
The hedgehog signaling pathway is essential for numerous processes during embryonic development. Members of the hedgehog family of secreted proteins control cell proliferation, differentiation and tissue patterning. The pathway was first deciphered in the fruit fly
Cyclopamine lactam analogs and methods of use thereof
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TECHNICAL FIELD
The present invention generally relates to cyclopamine analogs, pharmaceutical compositions thereof, and methods for using such analogs and compositions. These compounds and compositions can be useful for the treatment of hedgehog mediated disorders, such as cancer and
Cyclopamine lactam analogs and methods of use thereof
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TECHNICAL FIELD
The present invention generally relates to cyclopamine analogs, pharmaceutical compositions thereof, and methods for using such analogs and compositions. These compounds and compositions can be useful for the treatment of hedgehog mediated disorders, such as cancer and
Cyclopamine lactam analogs and methods of use thereof
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TECHNICAL FIELD
The present invention generally relates to cyclopamine analogs, pharmaceutical compositions thereof, and methods for using such analogs and compositions. These compounds and compositions can be useful for the treatment of hedgehog mediated disorders, such as cancer and
Heterocyclic cyclopamine analogs and methods of use thereof
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TECHNICAL FIELD
The present invention generally relates to cyclopamine analogs, pharmaceutical compositions thereof, and methods for using such analogs and compositions. These compounds and compositions can be useful for the treatment of hedgehog mediated disorders, such as cancer and
Heterocyclic cyclopamine analogs and methods of use thereof
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Prijavite se / prijavite se
TECHNICAL FIELD
The present invention generally relates to cyclopamine analogs, pharmaceutical compositions thereof, and methods for using such analogs and compositions. These compounds and compositions can be useful for the treatment of hedgehog mediated disorders, such as cancer and
Heterocyclic cyclopamine analogs and methods of use thereof
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Prijavite se / prijavite se
TECHNICAL FIELD
The present invention generally relates to cyclopamine analogs, pharmaceutical compositions thereof, and methods for using such analogs and compositions. These compounds and compositions can be useful for the treatment of hedgehog mediated disorders, such as cancer and
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