cysteic acid/nekroza

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EFFECTS OF EXCESS DIETARY CYSTEIC ACID, dl-METHIONINE, AND TAURINE ON THE RAT LIVER.

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1. Cysteic acid fed to albino rats as 12.5 to 15 per cent of the McCollum stock diet caused portal necrosis and cirrhosis of the liver within 2 weeks. Concentrations of cysteic acid of 6.25 per cent or less in the diet produced no liver lesions within 2 weeks. 2.dl-Methionine fed as 6.4 to 12.4 per

LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID.

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1. Rats fed l-cystine at excessive levels excrete large amounts of sulfate sulfur in the urine and develop liver necrosis and cirrhosis. 2. Rats fed dl-methionine at excessive levels excrete large amounts of sulfate sulfur, but do not develop liver necrosis and cirrhosis. 3. Rats fed cysteic acid at

Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site.

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The proteomics analysis reported here shows that a major cellular response to oxidative stress is the modification of several peroxiredoxins. An acidic form of the peroxiredoxins appeared to be systematically increased under oxidative stress conditions. Peroxiredoxins are enzymes catalyzing the

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