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The Association between Obesity and Severity of Dengue Hemorrhagic Fever in Children at Wangaya General Hospital.

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Dengue is a mosquito-borne disease caused by any one of four closely related Dengue virus (DENV 1-4). The clinical sign Dengue virus infection can vary from mild (mild febrile illness), Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) to Dengue Hemorrhagic Fever with shock (Dengue

Incidence and outcomes of dengue in a cohort of pregnant women from an endemic region of India: obesity could be a potential risk for adverse outcomes.

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The primary objectives of the study were to determine the incidence of dengue and outcomes associated with dengue among pregnant women.A prospective cohort study was done among 1579 antenatal women in an endemic region in India. Dengue immunoglobulin G

The association between obesity and dengue severity among pediatric patients: A systematic review and meta-analysis.

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Severe dengue infection often has unpredictable clinical progressions and outcomes. Obesity may play a role in the deterioration of dengue infection due to stronger body immune responses. Several studies found that obese dengue patients have a more severe presentation with a poorer prognosis.

The association of obesity and severe dengue: possible pathophysiological mechanisms.

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Dengue virus (DENV) is a medically important flavivirus and the aetiological agent of Dengue, a normally self-resolving febrile illness that, in some individuals, can progress into Severe Dengue (SD), a life-threatening disorder that manifests as organ impairment, bleeding and shock. Many different

The association between obesity and dengue virus (DENV) infection in hospitalised patients.

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Both obesity and DENV infections are growing public health concerns that have far-ranging socioeconomic effects, especially in developing countries. Despite the increasing prevalence of these conditions, there is a scarcity of data investigating the potential relationships between these two

Dengue-induced Acute Kidney Injury (DAKI): A Neglected and Fatal Complication of Dengue Viral Infection--A Systematic Review.

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Dengue Viral Infection (DVI) imperils an estimated 2.5 billion people living in tropical and subtropical regions. World Health Organization (2011) guidelines also classified dengue as 'Expanded Dengue Syndrome' to incorporate wide spectrum of unusual manifestations of dengue infection

Outcome of dengue hemorrhagic fever-caused acute kidney injury in Thai children.

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OBJECTIVE To examine the outcome of acute kidney injury (AKI) in children with dengue hemorrhagic fever (DHF), the cause(s) of AKI, and the risk of AKI and fatality. METHODS The medical records of patients age <15 years during 1989 to 2007 were reviewed. DHF-caused AKI and patients with DHF with no

Nutritional status impacts dengue virus infection in mice

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Background: Dengue virus (DENV) is estimated to infect 390 million people annually. However, few host factors that alter disease severity are known. Malnutrition, defined as both over- and undernutrition, is a growing problem worldwide

Relationship between body size and severity of dengue hemorrhagic fever among children aged 0-14 years.

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A hospital based case-control study was conducted from October 2002 to November 2003 among children aged 0-14 years at Queen Sirikit National Institute of Child Health (Children's Hospital), Bangkok, Thailand. This study focused on body size and severity of dengue hemorrhagic fever (DHF) in

Is dengue severity related to nutritional status?

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A retrospective review of dengue patients admitted to Queen Sirikit National Institute of Child Health (previously known as Children's Hospital) from 1995 to 1999 revealed 4,532 confirmed cases of dengue infection; 80.9% were dengue hemorrhagic fever (DHF) and 19.1% were dengue fever cases (DF).

Impact of Nutritional Status on the Severity of Dengue Infection Among Pediatric Patients in Southern Thailand

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Background: Given the lack of specific antiviral drugs and effective vaccine for dengue infection, factors such as host nutritional status that may alter disease progression require investigation. This study examined the relationship

Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.

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BACKGROUND The lack of a suitable animal model to study viral and immunological mechanisms of human dengue disease has been a deterrent to dengue research. RESULTS We sought to establish an animal model for dengue virus (DENV) infection and immunity using non-obese diabetic/severe combined

Characteristics and associated factors of acute kidney injury among adult dengue patients: A retrospective single-center study.

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Severe dengue cases have been increasingly reported in Thailand, and the under-reporting of acute kidney injury (AKI) in cases of dengue viral infection has become an obstacle in obtaining an accurate description of the true nature and epidemiology of AKI. Because AKI may lead to patient morbidity

Chymase is a Predictive Biomarker of Dengue Hemorrhagic Fever in Pediatric and Adult Patients.

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UNASSIGNED Most patients with dengue experience mild disease, dengue fever (DF), while few develop the life-threatening diseases dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). No laboratory tests predict DHF or DSS. We evaluated whether the serum chymase level can predict DHF or DSS

Association between nutritional status and dengue infection: a systematic review and meta-analysis.

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BACKGROUND Dengue infection has various clinical manifestations, often with unpredictable clinical evolutions and outcomes. Several factors including nutritional status have been studied to find the relationship with dengue severity. However, the nutritional status had conflicting effects on the

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