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Absence of progesterone effects on chlamydial genital infection in female guinea pigs.

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The effect of progesterone alone and in combination with estradiol was investigated in ovariectomized and gonadally intact female guinea pigs infected with the chlamydial agent of guinea pig inclusion conjunctivitis (GPIC). The course of the infection, as determined by the percentage of cells with

Genital tract abnormalities in female rats exposed to diethylstilbestrol in utero.

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Genital tract morphology in 14-month old female rats exposed prenatally to diethylstilbestrol (DES) was analyzed as part of an examination of the effects of transplacental exposure to DES on estrogen sensitive tissues. Pregnant Sprague-Dawley rats were injected with sesame oil alone or with DES in

Prostaglandin F2alpha upregulates uterine immune defenses in the presence of the immunosuppressive steroid progesterone.

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OBJECTIVE Uterine infections often develop in some livestock species during the first luteal phase postpartum. Exogenous prostaglandin F(2alpha) (PGF(2alpha)) induces luteolysis, reduces progesterone, and enables the uterus to resolve infections. However, the effects of PGF(2alpha) on luteal

Role of ovarian progesterone and potential role of prostaglandin F2alpha and prostaglandin E2 in modulating the uterine response to infectious bacteria in postpartum ewes.

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In sheep and cattle, the postpartum uterus is resistant to bacterial challenge until after corpora lutea develop. A 2 x 2 factorial arrangement of treatments was used to determine whether prostaglandins may mediate the effects of progesterone in transforming the postpartum uterus from resistant to

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