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5 rezultati
Evaluation of the effects of Eserine and JWH-133 on brain dysfunction associated with experimental endotoxemia.
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Sepsis is associated with neuronal damage and cognitive impairment, with the participation of pro-inflammatory cytokines and oxidative-nitrous stress. It is known that activated microglia plays a vital role in neuro-inflammation and neuro-degeneration. Thus, the objective of this study was to
Non-neuronal, but atropine-sensitive ileal contractile responses to short-chain fatty acids: age-dependent desensitization and restoration under inflammatory conditions in mice.
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Intestinal epithelial cells sense short-chain fatty acids (SCFAs) to secrete non-neuronal acetylcholine (ACh). However, the roles of luminalSCFAs and epithelialACh under normal and pathological conditions remain unknown. We examined ileal contractile responses toSCFAs at different ages and their
Anti-inflammatory and anticholinesterase activity of six flavonoids isolated from Polygonum and Dorstenia species.
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This study was aimed at investigating the anti-inflammatory and anticholinesterase activity of six naturally occurring flavonoids: (-) pinostrobin (1), 2',4'-dihydroxy-3',6'-dimethoxychalcone (2), 6-8-diprenyleriodictyol (3), isobavachalcone (4), 4-hydroxylonchocarpin (5) and 6-prenylapigenin (6).
Acetylcholinesterase Inhibitor from Anthocleista vogelii Leaf Extracts.
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BACKGROUND
Anthocleista vogelii (Planch) is used in folk medicine in conditions related to inflammation and oxidative stress.
OBJECTIVE
The leaf extracts were investigated for their bioactive constituents in our quest for novel compounds for the management of neurodegenerative
Essential oil and methanolic extract of Zataria multiflora Boiss with anticholinesterase effect.
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One of the most common strategies in the treatment of cognitive disorders is enhancing the acetylcholine level in the brain through the inhibition of acetylcholinesterase. Despite the effectiveness of current modern drugs, more attention has been paid for finding new anticholinesterase agents from
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