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Modulation of Chloride Channel Functions by the Plant Lignan Compounds Kobusin and Eudesmin.
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Plant lignans are diphenolic compounds widely present in vegetables, fruits, and grains. These compounds have been demonstrated to have protective effect against cancer, hypertension and diabetes. In the present study, we showed that two lignan compounds, kobusin and eudesmin, isolated from
Flos Magnoliae Inhibits Chloride Secretion via ANO1 Inhibition in Calu-3 Cells.
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Flos Magnoliae (FM, Chinese name: Xin-yi) is an oriental medicinal herb commonly used for symptomatic relief from allergic rhinitis, sinusitis, and headache, including in traditional Chinese and Korean medicine formulations. FM inhibits histamine release from mast cells and cytokine secretion from T
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