6 rezultati
Arterial hypertension is very common and occurs often in patients with haemophilia A (HA) and von Willebrand disease (VWD) due to their increased life expectancy. Bleeding complications in haemophilia and von Willebrand patients with hypertension so far are not well evaluated. Even data regarding
BACKGROUND
As the population of patients with haemophilia (PWH) ages, healthcare providers are required to direct greater attention to age-related co-morbidities. Low bone mineral density (BMD) is one such co-morbidity where the incidence not only increases with age, but also occurs with greater
The clinical picture of haemophilia A patients is often characterised by recurrent bleedings, in particular joint bleeds. Thus far, long-term data on the outcome of haemophilia A patients are scarce as regards the development of target joints, joint replacement, lost days from school or work due to
Inhibitor formation is a serious complication of factor VIII (FVIII) replacement therapy for the X-linked bleeding disorder haemophilia A and occurs in 20%-30% of patients. No prophylactic tolerance protocol currently exists. Although we reported oral tolerance induction using FVIII domains
Hemophilia A is the X-linked bleeding disorder caused by deficiency of coagulation factor VIII (FVIII). To address serious complications of inhibitory antibody formation in current replacement therapy, we created tobacco transplastomic lines expressing FVIII antigens, heavy chain (HC) and C2, fused
OBJECTIVE
The prevalence and predisposing factors of substance dependency in 100 Iranian hemophilic patients were investigated.
METHODS
A confidential questionnaire and DSM-IV criteria were used. Data were gathered from 100 randomly selected hemophilic patients.
RESULTS
The mean age of studied