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herpes genitalis/seizures

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Herpes simplex virus vectors overexpressing the glucose transporter gene protect against seizure-induced neuron loss.

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We have generated herpes simplex virus (HSV) vectors vIE1GT and v alpha 4GT bearing the GLUT-1 isoform of the rat brain glucose transporter (GT) under the control of the human cytomegalovirus ie1 and HSV alpha 4 promoters, respectively. We previously reported that such vectors enhance glucose uptake

Herpes simplex virus type 1 inoculation enhances hippocampal excitability and seizure susceptibility in mice.

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Herpes simplex virus type 1 (HSV-1) is the major pathogen related to epilepsy. However, little is known about the pathogenesis of HSV-1-associated epilepsy. Here, we report that corneal inoculation of mice with HSV-1 induces acute spontaneous behavioural and electrophysiological seizures and

Neurovirulence of two clonally related herpes simplex virus type 1 strains in a rabbit seizure model.

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Herpes simplex virus type 1 (HSV-1) strains vary widely with regard to neurovirulence, but their tropism for specific central nervous system structures and their ability to induce seizures are poorly defined. We have used the clonally related +GC and -GC strains of HSV-1 to define the

Neurovirulence in an experimental focal herpes encephalitis: relationship to observed seizures.

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An animal model of focal herpes simplex encephalitis was used to study several strains of type-1 herpes simplex virus. Rabbits were inoculated in the olfactory bulb by a standardized technique. Virus strains resulting in mortality of greater than 70% produced seizures of 3 types, and all animals

Reverse crossed cerebellar diaschisis in partial complex seizures related to herpes simplex encephalitis.

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Tc-99m HMPAO brain SPECT was performed in a patient who had partial complex seizures for 1 year after successful acyclovir treatment of biopsy-proven herpes simplex encephalitis 2 years earlier. In spite of antiepileptic medications, her seizures were intractable and occurred daily. Tc-99m HMPAO was

Central nervous system herpes simplex virus infection in afebrile children with seizures.

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Central nervous system herpes simplex virus infection is suspected in patients presenting with acute-onset seizures and lethargy. The potential neurologic sequelae from untreated herpes infection can prompt empirical acyclovir therapy, even in afebrile subjects. The objectives of this study were to

Risk of bacterial or herpes simplex virus meningitis/encephalitis in children with complex febrile seizures.

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OBJECTIVE To estimate the rates of bacterial meningitis and herpes simplex virus (HSV) encephalitis in children presenting with complex febrile seizures. METHODS Health records from 2002 to 2006 of all children 6 months to 6 years with a discharge diagnosis from the Hospital for Sick Children
Although uncommon, the association of chronic encephalitis with epilepsy is well recognized. While a viral etiology has been suspected based on the morphology, to date no virus has been successfully cultured from the brain in patients with Rasmussen's encephalitis. We describe the pathologic

Simultaneous detection of herpes simplex virus 1 and 2 in the cerebrospinal fluid of a patient with seizures and encephalitis.

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We report a case of a 62-year-old female with seizures and encephalitis. Molecular testing of the patient's cerebrospinal fluid was positive for both herpes simplex virus 1 and 2 (HSV-1 and HSV-2). To our knowledge, this is the first report of simultaneous detection of HSV-1 and HSV-2 in

[A study of the relationship between initial febrile seizures and human herpes virus 6, 7 infections].

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The DNA detection of human herpes virus (HHV) 6, 7 was performed in the patients who visited to the Nakano children's hospital because of their initial febrile seizures (FS). Those patients included 35 boys and 21 girls under 3 years of age (mean: 1 year 4 months). DNAs of HHV 6, 7 in the
OBJECTIVE To determine whether herpes simplex virus causes monofocal epilepsy and to assess the presence of herpes simplex virus 1 (HSV-1) and HSV-2 in surgical specimens from patients with epilepsy by using polymerase chain reaction and Southern blot analysis. BACKGROUND Herpes simplex virus is a

[Complicated febrile convulsion vs herpes-encephalitis].

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Since Acyclovir is available a sufficient treatment of herpes simplex virus (HSV) encephalitis exists. Febrile convulsions may occur as the initial manifestation of an encephalitis, particularly of an HSV encephalitis. Within 25 months out of 151 children with febrile convulsions five children with

A case report of neonatal convulsions due to maternal herpes gestationis.

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Herpes gestationis is a rarely seen autoimmune vesiculobullous and pruritic dermatosis of pregnancy. Neonatal morbidity associated with maternal herpes gestationis is controversial. The authors report the first case of neonatal convulsion with abnormal electroencephalography findings and transient

Human Herpes Virus Type 6 and Febrile Convulsion.

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OBJECTIVE Febrile Convulsion (FC) is occurred in 6 months to 5 yr old children. The aim of this study was to investigate the prevalence of HHV-6 infection in FC admitted patients of Bandar Abbas Children Hospital, southern Iran. METHODS In a cross-sectional study, 118 children aged 6-60 months who

Parechovirus-A3 encephalitis presenting with focal seizure mimicking herpes simplex virus infection.

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Febrile neonates and young infants presenting with seizure require immediate evaluation and treatment. Herein we experienced two young infants with parechovirus-A3 (PeV-A3) encephalitis, initially presented with focal seizure suspecting herpes simplex virus (HSV)
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