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hinesol/lancea

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Biotransformation of hinesol isolated from the crude drug Atractylodes lancea by Aspergillus niger and Aspergillus cellulosae.

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Biotransformation of the sesquiterpene alcohol hinesol (1) with spasmolytic activity, which was prepared from the rhizome of Atractylodes lancea, was carried out by Aspergillus niger and Aspergillus cellulosae IFO 4040. Compound 1 was easily converted to compounds 2-9 by A. niger, and compounds 10
Hinesol is a unique sesquiterpenoid isolated from the Chinese traditional medicine, Atractylodes lancea rhizome. In a previous study, we screened various natural products in human leukemia HL-60 cells and identified an essential oil fraction from A. lancea rhizome that exhibited apoptosis-inducing

Evaluation of heritability of β-eudesmol/hinesol content ratio in Atractylodes lancea De Candolle.

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Atractylodes lancea De Candolle is a medicinal plant distributed in East Asia. Its rhizome has been used as an important crude drug in traditional Chinese and Japanese medicines for the treatment of numerous diseases and disorders. In recent years, the demand for mass production of the
OBJECTIVE To develop a GC method for simultaneous determination of 4 compounds (atractylone, hinesol, beta-eudesmol and atractylodin) in Atractylodes lancea. METHODS A HP-1 capillary column (0.25 mm x 30 m, 0.25 microm) was used. The detector was FID:Inlet temperature was 250 degrees C. The detector
Lung cancer (especially, non-small cell lung cancer [NSCLC]) is one of the most malignant cancers in the world. Hinesol is the major component of the essential oil of Atractylodes lancea (Thunb.) DC and possesses the most promising anticancer function. However, the effects and molecular mechanism of

A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.

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To clarify the variation in the pharmacologically active components of the essential oil contained in the rhizomes of Atractylodes lancea and A. chinensis growing in China, we transplanted the rhizomes of the wild plants from 18 populations, including A. koreana, in the same experimental field.

Seven herbs against the stored product insect: Toxicity evidence and the active sesquiterpenes from Atractylodes lancea.

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In this work, the essential oils (EO) were extracted from seven typical Chinese herbs, and their repellent and contact toxicities against Tribolium castaneum adults (red flour beetles) were evaluated. The experimental results showed that the above EOs presented the various levels of repellent and

[Studies on chemical constituents in essential oil from wild Atractylodes lancea in dabie mountains].

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The chemical constituents in essential oil of wild Atractylodes lancea (Thumb.) DC. from Dabie Mountains were studied. The essential oil was extracted by simultaneous distillation and extraction equipment and analyzed by gas chromatography-mass spectrometry method. 49 compounds were identified and

[GC-MS analysis of essential oils from rhizomes of Atractylodes lancea (Thunb.) DC. and A. chinensis (DC.) Koidz].

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OBJECTIVE To analyze the constituents from the rhizomes of Atractylodes lancea and A. chinensis in essential oils. METHODS GC-MS method was used. RESULTS 32 and 29 compounds were identified respectively. CONCLUSIONS The main constituents in the essential oils from the rhizome of A. chinensis are

Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea.

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Rhizomes of Atractylodes lancea are used in traditional Japanese medicine (Kampo) and Chinese medicine to treat numerous diseases and disorders because they contain many pharmacologically active compounds. The major active compounds in A. lancea are essential oil compounds such as β-eudesmol,

Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures.

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Two strains of autotetraploid plants of Atractylodes lancea DC. (Compositae) were raised from the in vitro colchicine-treated shoot cultures, and field trials were performed to evaluate their growth and the amount of essential oil components in the rhizome in comparison with the corresponding

[The naphtha composing characteristics of geoherbs of Atractylodes lancea].

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OBJECTIVE To find the chemical diversity and characteristics of A. lancea on two levels--individuals and populations, and to discover the chemical essentials for forming geoherbs. METHODS 47 rhizomes of A. lancea were collected in 7 populations, and 6 naphtha components (1. elemol, 2. hinesol, 3.

[Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea].

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OBJECTIVE To investigate the effects of different amounts of lime on yield and quality of Atractylodes lancea, and to provide reference for the herb growing site soil improvement and self-poisoning ease. METHODS Add different gradients of lime, and then measure their growth targets, yield and four

[Fingerprint of volatile oil of Atractylodes lancea by GC-MS].

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To study the fingerprint of the volatile oil of Atractylodes lancea (Thunb.) DC., and to offer the characteristic data for the quality evaluation, GC-MS analysis was performed for 17 samples of different areas used as Atractylodes lancea (Thunb.) DC. Nine kinds of same components were selected. TIC
Cholangiocarcinoma (CCA) is the primary type of bile duct cancer with high morbidity and mortality, particularly in patients with advanced-stage disease. Treatment of CCA remains unsatisfactory due to the lack of sensitive and specific diagnostic tool for early detection as well as
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