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hirsutism/upala

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An update on the pathogenesis, inflammation, and metabolism in hirsutism and polycystic ovary syndrome.

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Hirsutism is a common endocrine disorder, defined as increased growth of terminal hairs in a male pattern. Hirsutism is most often caused by polycystic ovary syndrome (PCOS), whereas only 5% patients are diagnosed with rare endocrine diseases. PCOS may be considered a multiorgan disease causing not
OBJECTIVE To investigate whether the systemic inflammation induced by chlamydial infections might be associated with symptoms of polycystic ovary syndrome (PCOS). METHODS Nested case-control study. METHODS A questionnaire including questions about hirsutism and oligo-amenorrhea was distributed to a

Full-length visfatin levels are associated with inflammation in women with polycystic ovary syndrome.

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BACKGROUND Polycystic ovary syndrome (PCOS) is the most common gynaecological endocrinopathy characterized by oligomenorrhea, amenorrhoea, clinical and/or biochemical hyperandrogenism and polycystic ovaries. Abdominal deposition of excess body fat and metabolic diseases like insulin resistance and
Polycystic ovary syndrome (PCOS) is a disorder which concern even 5-10% of women in reproductive age. PCOS is a cause of hyperandrogenism and menstrual disorders with chronic anovulation. The most common clinical symptoms observed in PCOS are hirsutism, acne and obesity. Patients with PCOS often
OBJECTIVE To investigate if colchicine is valuable in the treatment of Graves' ophthalmopathy (GO), we compared its effect with prednisone in 22 patients during the inflammatory phase of GO. METHODS All patients, similar in age, sex and smoking habits, were euthyroid for at least 3 months and
OBJECTIVE Hirsutism is most often caused by polycystic ovary syndrome (PCOS). PCOS patients are characterized by insulin resistance, abdominal obesity and low-grade inflammation. Insulin sensitizing treatment reduces the inflammatory state, but the effect on serum levels of migration inhibitor
The aim of this study was to evaluate the effect of the co-administration of carnitine and chromium on mental health, hormonal, inflammatory and genetic parameters in women with PCOS.This randomized, double-blinded, placebo-controlled clinical trial was

The association of dynamic thiol-disulfide homeostasis and inflammatory markers in patients with polycystic ovary syndrome.

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Polycystic ovary syndrome (PCOS) is a common hormonal disorder among women of reproductive age characterized by irregular menstruation and hirsutism and is associated with an increased risk for cardiovascular diseases. Increased inflammatory response and oxidative stress may also

Cyclosporin treatment in three children with chronic inflammatory demyelinating neuropathy.

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Chronic inflammatory demyelinating neuropathy is an uncommon acquired polyneuropathy in children. Oral prednisolone, intravenous methyl prednisolone, and intravenous immunoglobulin are its main initial therapies. In patients resistant to these modalities, other immunosuppressants can be used. We

[Efficacy and safety of cyclosporine in the treatment of inflammatory bowel disease in children - a retrospective study].

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OBJECTIVE the aim of this study was to report single centre experience with cyclosporine used in treatment of children with inflammatory bowel disease with regard to safety and efficacy. METHODS retrospective analysis included 23 patients, 21 with ulcerative colitis and 2 with Crohn's disease, aged

Cyclosporine: a therapy in inflammatory eye disease.

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Severe uveitis is a relatively common and difficult clinical management problem in ophthalmology. Recently, cyclosporine-A (Cs-A) has been shown to be of therapeutic benefit in the management of sight threatening inflammatory eye disease. In order to examine the efficacy and long term safety of
OBJECTIVE To determine the additive renal effects of nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclosporine A (CYA) in patients with rheumatoid arthritis (RA) and to determine the effects of CYA on active RA. METHODS Eleven patients with RA refractory to other agents were treated separately
BACKGROUND Cyclosporine-induced side-effects such as gum enlargement and hirsutism potentially limit its effectiveness as a calcineurin-antagonist if these effects contribute to a lack of compliance. Although the differences in incidence of these effects are widely recognized, few studies are

The role of low-grade inflammation in the polycystic ovary syndrome.

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PCOS is not only the most frequent cause of oligomenorrhea in young women, but also a metabolic disorder characterized by insulin resistance, glucose intolerance, dyslipidemia, and obesity, especially the visceral phenotype. PCOS represents a broad spectrum of endocrine and metabolic alterations
BACKGROUND Polycystic ovary syndrome (PCOS), a common endocrine disorder, is associated with infertility, menstrual dysfunction, hirsutism and frequent miscarriages. Insulin resistance, as a major cause of PCOS, represents a disorder with increase in inflammatory markers and risk of type 2 diabetes.
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