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hispidulin/scutellaria

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New phenolics from the root of Scutellaria prostrata JACQ. ex BENTH.

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Scutellaria prostrata (Lamiaceae), a perennial herb growing as a lonely species in Kashmir, Himalayas, was subjected to repetitive column and flash chromatographic isolation for its chemical documentation-cum-bioevaluation. The methanolic extract of S.prostrata afforded the isolation of ten
Ultra high performance liquid chromatography (UHPLC) coupled with a hybrid quadrupole time-of-flight mass spectrometry (QTOF-MS) was used to separate and identify the compounds in Scutellaria indica L. Fragmentation patterns of these compounds were investigated by the UHPLC-QTOF-MS technique in both

Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers.

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Prolyl oligopeptidase (POP) is a serine protease highly expressed in the brain that hydrolyses peptide bonds at the carboxyl terminal of prolyl residues. There is evidence that this enzyme participates in several functions of the central nervous system. Scutellaria racemosa Pers demonstrated

Antitumor activity of chloroform fraction of Scutellaria barbata and its active constituents.

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Scutellaria barbata (SB) is widely used as an antitumor agent in China, but the antitumor components of SB are still unclear. The antitumor activity of various fractions of an ethanol extract of SB was studied in six human malignant cell lines. Bio-based assays showed that non-polar and low-polar
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