hyperparathyroidism/kalij

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Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls

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Hereditary hypophosphatemia (XLH) is a rare, inherited disease. Loss-of-function mutation in PHEX results in excess fibroblast growth factor 23 (FGF23) production and manifests as rickets in children and osteomalacia in adults. FGF23 is a hormone that reduces renal phosphate reabsorption, decreases

Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism

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To conduct a double-blinded, placebo-controlled, randomized intervention study to investigate whether mineralocorticoid receptor (MR) antagonism, alone or in combination with cinacalcet, is an effective therapy for primary hyperparathyroidism (P-HPTH). Hypothesis: MR antagonism, as a monotherapy or

Effect of Restriction of Foods Containing Phosphorus Additives

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The consumption of foods which contain phosphorus by patients on hemodialysis should be monitored in order to reflect the current reality, due to the increase in ingestion of industrialized foods rich in phosphorus additives. Data from studies performed in the USA shows a reduction in phosphatemia

Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients

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The prospective pilot study is designed to evaluate vitamin D status pre-operatively and post-operatively in 37 female patients undergoing either Roux-en Y gastric bypass or sleeve gastrectomy at The Methodist Hospital with 32 patients expecting to complete the 12 week trial. Women scheduled for

Parathyroid Hormone (PTH) Homeostasis in Bartter Syndrome

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The parathyroid glands play a pivotal physiological function by maintaining blood calcium levels, specifically blood ionized calcium concentrations, within a very narrow range. They do so by modulating the minute-to-minute release of parathyroid hormone (PTH) into the circulation. Such changes have

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