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hypocapnia/nekroza

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11 rezultati

Hypocarbia as a pathogenic factor in pontosubicular necrosis.

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In neonates pontosubicular necrosis (PSN) is one of the patterns of acute brain injury, the sites of maximum damage being the basis pontis and the subiculum of the hippocampus. A retrospective clinical and pathological study was performed on 16 preterm and 2 term neonates with PSN and compared with

Neuron death and glial response in pontosubicular necrosis. The role of the growth inhibition factor.

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OBJECTIVE Fluorochrome and immunohistochemical studies were performed on neonates with pontosubicular necrosis (PSN), aged 26 - 42 weeks of gestation (GW), compared with preterm and term controls aged from 10 GW to 3 months of age. RESULTS A fluorochrome study using a confocal microscope revealed
OBJECTIVE During gram-negative bacteremia (GNB), tumor necrosis factor-alpha (TNF-alpha) is a critical early mediator of host defense, whose overexpression can initiate acute lung injury, multiple organ failure, and death. In this study we evaluated the ability of a chimeric fusion protein

[Hypoxic-ischemic brain damage: detection of early stage].

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The type of hypoxic-ischemic brain damage is determined by the distribution of lesions, which has different mechanism in each. Neuroimaging is important for detection of the lesions, but morphological changes appear 12 hours after hypoxic episodes even in neuropathology. Hemodynamic, biochemical and

Etiologies and distribution of neonatal leukomalacia.

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Neonatal leukomalacia was classified into 4 groups: focal (F), widespread (W), diffuse (D), and multicystic encephalomalacia (MCE) according to the distribution of ischemic necrosis in the cerebral hemisphere. The highest and lowest values of PaCO2, PaO2, and pH and the lowest systolic and diastolic

[Cerebral palsy: new pathogenetic concepts].

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OBJECTIVE To review the current knowledge pertaining to the new pathogenetic aspects of cerebral palsy (CP). METHODS CP is a group of static, heterogeneous clinical syndromes, characterized by abnormal postural mechanisms and motor activities. Its prevalence in industrialized countries is 2 2.5/1000
Cyclophosphamide-induced neutropenia exacerbates septic shock and multiple organ injury in conscious rats during Escherichia coli (EC) bacteremia despite antibiotics and fluid administration. We hypothesized that such shock and inflammatory organ injury would be mitigated by rBPI23's microbicidal

Hypocapnic hypothesis of Leigh disease.

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Leigh syndrome (LS) is a neurogenetic disorder of children caused by mutations in at least 75 genes which impair mitochondrial bioenergetics. The changes have typical localization in basal ganglia and brainstem, and typical histological picture of spongiform appearance, vascular proliferation and

A CT method to measure hemodynamics in brain tumors: validation and application of cerebral blood flow maps.

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OBJECTIVE CT is an imaging technique that is routinely used for evaluating brain tumors. Nonetheless, imaging often cannot show the distinction between radiation necrosis and neoplastic growth among patients with recurrent symptoms after radiation therapy. In such cases, a diagnostic tool that

[A case of sarcoidosis presenting with high fever and acute respiratory failure].

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A 55-year-old man was admitted with complaints of remittent fever (39 degrees C) and dyspnea on exertion which began ten days previously. His family and past histories were non-contributory for diagnosis except his occupation as a stone mason for 26 years. The chest X-ray film taken on admission

The effects of CO2 on cytokine concentrations in endotoxin-stimulated human whole blood.

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OBJECTIVE Hypercapnia is known to modulate inflammation in lungs. However, the effect of hypocapnia and hypercapnia on blood cytokine production during sepsis is not well understood. We hypothesized that CO2 modulates ex vivo inflammatory cytokine production during endotoxin stimulation. To test
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