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Cucurbitacin IIb, a steroidal triterpene from Ibervillea sonorae induces antiproliferative and apoptotic effects on cervical and lung cancer cells.

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Chemical studies on Ibervillea sonorae (S. Watson) Greene root led to isolation and chemical characterization of diverse cucurbitacin triterpenoid compounds such as kinoin A, B, C, and their glucosides. In previous studies, we demonstrated that kinoin A inhibits the cell proliferation on diverse

Quantitative analysis of cucurbitane-type triterpenes in Ibervillea sonorae extracts: Relationship study with their antiproliferative activity

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Ibervillea sonorae (Cucurbitaceae) is a Mexican plant commonly used by local population for its hypoglycaemic activity. Root extracts showed also other different biological activities, including antimicrobial, antifungal, antioxidant and anti-inflammatory activity. Main components of this plant are

Cucurbitacin IIb from Ibervillea sonorae Induce Apoptosis and Cell Cycle Arrested via STAT3 Inhibition.

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Cucurbitacin IIb (CIIb) from Ibervillea sonorae has great capacity to suppress the proliferation of cancer cells and induce apoptosis. In this study, the molecular mechanisms related to the antiproliferative and apoptosis induction capacity of CIIb (derivate from Ibervillea sonorae) in

Cytotoxic activity of four Mexican medicinal plants.

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Ibervillea sonorae Greene, Cucurbita ficifolia Bouché, Tagetes lucida Cav and Justicia spicigera Scheltdd are Mexican native plants used in the treatment of different illnesses. The ethanolic extract of J. spicigera and T. lucida as well as aqueous extracts from I. sonorae, C. ficifolia, T. lucida

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