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lanolin/hipersenzitivnost

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The lanolin paradox.

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Several puzzling aspects of the use of lanolin are discussed as "lanolin paradoxes', in analogy with the 'paraben paradoxes'. Lanolin in topical therapeutic agents sensitizes a high proportion of patients, whereas the same lanolin is 'safe' in cosmetics so widely used by millions of individuals.

Allergy due to topical medications in chronic otitis externa and chronic otitis media.

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Thirty-four patients suffering from chronic otorrhoea were tested for delayed type contact allergy. Patch testing showed a relevant positive reaction in 19 patients (56%). The most frequent allergens were aminoglycosides with neomycin and framycetin as major offenders. Other antimicrobial agents

Allergy to ingredients of vehicles.

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Common ingredients of vehicles such as perfumes, antibacterial agents, emulsifiers and other surface active agents, propylene glycol, lanolin and wool alcohols were tested in eczema patients over a three-year period. Perfume allergy was detected in 3.6% of the cases, sensitivity to thiomersal in 2%,

Allergic contact dermatitis in children: review of the past decade.

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Allergic contact dermatitis (ACD) is a type IV delayed hypersensitivity reaction. During the last decade, there has been a heightened awareness of this disease in the pediatric population. The gold standard for diagnosis is patch testing. The prevalence of positive patch tests in referred children

Contact hypersensitivity and allergic contact dermatitis among school children and teenagers with eczema.

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BACKGROUND Patch testing is an essential procedure in the investigation of eczema in children. OBJECTIVE To analyse the frequency of contact hypersensitivity and allergic contact dermatitis among Polish children with eczema. METHODS During an allergy screening programme involving 9320 children aged
Periorbital dermatitis is common and can be due to the external use of ophthalmic drugs. We evaluated patch test results of the Information Network of the Departments of Dermatology. During a 5-year period (1995-99), of a total 49,256 patch-tested patients, 1053 (2.1%) were eventually diagnosed as
Several contact allergens are tested at concentrations which might cause irritant reactions. In this study we investigated whether the reactivity to a standard irritant is useful in identifying subjects with hyperreactive skin yielding a higher rate of doubtful or irritant reactions. Sodium lauryl

Testing a purified lanolin preparation by a randomized procedure.

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Patients with a previous contact allergy to lanolin (wool alcohols and/or Amerchol L 101) were patch tested 1 to 4 years later with lanolin allergens, as well as purified anhydrous lanolin contained in a commercial cream. At this retest, only 20 out of 33 patients with a previous contact allergy to

Lanolin with reduced sensitizing potential. A preliminary note.

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The allergens of lanolin appear to lie in the content of natural free fatty alcohols rather than in the total alcohols as hitherto supposed. The detectable incidence of allergy is increased by the simultaneous presence of detergent. Amongst selected lanolin-sensitive skin patients, removal of both

Clinical relevance of positive patch test reactions to lanolin- a ROAT study

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Background: Lanolin is often included when patch testing for common contact allergens. The clinical relevance of a positive patch test reaction to lanolin markers though is still a subject for debate.

Positive patch test reactions to lanolin: cross-sectional data from the north american contact dermatitis group, 1994 to 2006.

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BACKGROUND The prevalence of lanolin sensitivity in referred patients is less than 4%. OBJECTIVE To (1) describe patients with positive patch-test reactions to lanolin, (2) determine clinical and occupational relevance associated with reactions to lanolin and common sources, and (3) examine the

Contact allergy to special and standard allergens in patients with venous ulcers.

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The aim of the study was to determine the prevalence of contact sensitivity in patients with leg ulcers, and possible difference in the rate of contact hypersensitivity to standard series of allergens used in patch testing, and to particular topical agents used in local therapy of leg ulcers in
BACKGROUND Food allergy is strongly associated with atopy. This retrospective study investigates whether atopic status affects responses to contact allergens also found in food. We compared incidences of atopic dermatitis/eczema (AD) in subjects who were patch-test positive (PT+) to diallyl

Contact allergy to topical medicaments becomes more common with advancing age: an age-stratified study.

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Eczema is common in the elderly people who often use topical medicaments. Previous studies in the elderly people have noted allergic positive patch tests in between 43% and 64% of those tested. We set out to assess whether medicament contact allergies are more common in elderly patients. We
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