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ligularia oligonema/reductase

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Pyrrolizidine alkaloid clivorine-induced oxidative stress injury in human normal liver L-02 cells.

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Clivorine is an otonecine-type pyrrolizidine alkaloid isolated from the traditional Chinese medicine Ligularia hodgsonii Hook. Pyrrolizidine alkaloids (PAs) are well-known hepatotoxins widely distributed around the world. The present study sought to evaluate clivorineinduced oxidative injury in

Ligularia fischeri leaf extract prevents the oxidative stress in DBA/1J mice with type II collagen-induced arthritis.

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The generation of free radicals has been implicated in the causation of several diseases and compounds that can scavenge free radicals have great potential in ameliorating these disease processes. The present study was aimed to investigate the possible antioxidant potential of Ligularia fischeri
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