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microphthalmos/kalij
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Mitf links neuronal activity and long-term homeostatic intrinsic plasticity.
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Neuroplasticity forms the basis for neuronal circuit complexity and differences between otherwise similar circuits. We show that the Microphthalmia-associated transcription factor (Mitf) plays a central role in intrinsic plasticity of olfactory bulb (OB) projection neurons. Mitral and tufted
Hexavalent chromium-induced congenital abnormalities in chick embryos.
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The embryotoxic and teratogenic potential of hexavalent chromium was evaluated in chick embryos. Different concentrations of aqueous solution of potassium dichromate ranging from 1.00 to 100.00 microg per egg were injected into chick eggs before incubation. A dose-dependent embryonic mortality was
Cochlear melanocytes and MITF signaling.
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Melanocytes occur not only in the skin and eyes but in the cochlea, where they exist as intermediate cells of the stria vascularis. Intermediate cells play an important role for cochlear function: Na+K+-ATPase and potassium channels of intermediate cells are essential for production of endocochlear
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