mitral valve insufficiency/triglyceride

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PPAR-gamma agonist rosiglitazone ameliorates ventricular dysfunction in experimental chronic mitral regurgitation.

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Previously we reported that the beneficial effects of beta-adrenergic blockade in chronic mitral regurgitation (MR) were in part due to induction of bradycardia, which obviously affects myocardial energy requirements. From this observation we hypothesized that part of the pathophysiology of MR may

Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification.

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BACKGROUND Mitral annular calcium (MAC), commonly identified by cardiac imaging, is associated with cardiovascular events and predisposes to the development of clinically important mitral valve regurgitation and mitral valve stenosis. However, its biological determinants remain largely

Frequency of ischemic mitral regurgitation after first-time acute myocardial infarction and its relation to infarct location and in-hospital mortality.

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BACKGROUND Ischemic mitral regurgitation (IMR) is a common complication after acute myocardial infarction (AMI). We aimed to investigate the frequency of IMR following first-time AMI and its association with infarct location, in-hospital mortality, and complications. METHODS From September 2011 to

Warfarin or aspirin in embolism prevention in patients with mitral valvulopathy and atrial fibrillation.

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BACKGROUND Atrial fibrillation (AF) associated to rheumatic mitral valve disease (RMVD) increases the incidence of thromboembolism (TE), with warfarin being the standard therapy, in spite of difficulties in treatment adherence and therapeutic control. OBJECTIVE To compare the effectiveness of

Dietary intervention reduces left atrial enlargement in dogs with early preclinical myxomatous mitral valve disease: a blinded randomized controlled study in 36 dogs.

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Myxomatous mitral valve disease (MMVD), the most common naturally-occurring heart disease in dogs, is associated with alterations in energy metabolism, oxidative stress and inflammation. Energy deprivation plays a causal role in the development of heart failure. This study was designed

[Association of Atrial Fibrillation with Coronary Lesion in Ischemic Heart Disease Patients].

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to find out whether atrial fibrillation (AF) in patients with ischemic heart disease (IHD) is related to some definite localization or extent of coronary artery lesions or type of coronary circulation.We compared data of clinical, laboratory, and

[Ocular Manifestation of Mucopolysaccharidosis I-S (Scheie's Syndrome)].

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BACKGROUND Bilateral stromal corneal opacifications are a differential diagnostical challenge to identify associated systemic diseases. METHODS A 47-year old civil engineer (height 167 cm) with bilateral stromal corneal clouding presented with visual loss for the last 27 years: VA 20/100 OD and

Prevalence of heart disease in older women in a nursing home.

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The prevalence of coronary artery disease (CAD) and the incidence of new coronary events are similar in older men and women. Independent risk factors for new coronary events in older women include age, prior CAD, cigarette smoking, hypertension, diabetes mellitus, high serum total cholesterol and

Echocardiographic findings, lipids and lipoprotein(a) in patients with systemic lupus erythematosus.

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Cardiac involvement, evaluated by echo-doppler-cardiography, occurred in 41 of 50 (82%) patients with systemic lupus erythematosus (SLE). Valvular pathology with aortic cusp sclerosis was the most prevalent finding irrespective of age. This finding, suggestive of atherosclerotic heart disease, was

Chylopericardium following mitral valve replacement.

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A 49-year-old man with mitral regurgitation developed chylopericardium after mitral valve replacement. On postoperative day (POD) 1, the patient was started on a regular diet. On POD 2, drainage from retrosternal and intrapericardial tubes increased, becoming turbid and milky. Because the

Regurgitant valvular disease prevalence and progression found on echocardiogram in military aviators.

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BACKGROUND The prevalence, progression rates, and outcomes affecting aviator valvular heart disease have not been extensively studied. METHODS The U.S. Air Force (USAF) School of Aerospace Medicine's Clinical Sciences Database was used to determine prevalence and progression rates for regurgitant

Cardiac Manifestations in Systemic Lupus Erythematosus: Clinical Correlates of Subclinical Echocardiographic Features.

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This study aims to correlate subclinical echocardiographic features with the clinical, laboratory, and therapeutic profiles of the patients to characterize risks for systemic lupus erythematosus (SLE) cardiac diseases.The study included 59 SLE patients.

Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study.

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Aortic valve stenosis is commonly considered a degenerative disorder with no recommended preventive intervention, with only valve replacement surgery or catheter intervention as treatment options. We sought to assess the causal association between exposure to lipid levels and risk of

Prevalence and correlates of mitral valve prolapse in a population-based sample of American Indians: the Strong Heart Study.

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OBJECTIVE Mitral valve prolapse is heritable and occurs frequently in the general population despite associations with mitral regurgitation and infective endocarditis, suggesting that selective advantages might be associated with mitral valve prolapse. METHODS Clinical examination and 2-dimensional

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