myoma/phosphatase

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Alkaline phosphatase from human uterine myoma. II. Kinetic and immunological properties.

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Thermostability of the purified alkaline phosphatase derived from human uterine muscle and myoma was established before and after desialization. Both enzymes were inhibited by sucrose, glucose and maltose in proportion to the carbohydrate concentration. L-Homoarginine inhibits the myoma enzyme in

Alkaline phosphatase from human uterine myoma. I. Purification and some properties.

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Alkaline phosphatase from human uterine myoma was purified to homogeneity by butanol extraction, acetone precipitation, column chromatography on DEAE-cellulose, QAE-Sephadex and Con-A-Sepharose, gel filtration on Sephadex G-200 and preparative electrophoresis. The relative molecular mass (145 000),

SHP-2 phosphatase promotes cervical cancer cell proliferation through inhibiting interferon-β production.

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OBJECTIVE The aim of this study was to explore the effect of Src-homology-2-domain-containing protein, tyrosine phosphatase 2 (SHP-2) on the proliferation of cervical cancer cells. METHODS A total of 45 patients with cervical cancer (stage I-III), 32 with cervical intraepithelial neoplasia and 20

[A study on alkaline phosphatase in cervical mucus using disc electrophoresis].

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A simple filter-disc-absorption technique for sampling human cervical mucus had been developed by colleagues of author. Using this technique, electrophoretic patterns of proteins and phosphorylase in cervical mucus had been reported. In this presentation, I report isoenzyme patterns of alkaline

[Immunological disorders in patients with uterine myomas].

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The investigations covered a group of 20 patients with uterine myomas aged 38 to 57 years. The control group consisted of 20 healthy women. The following indices were used in the assessment of non-specific immunity: 1) determination of the total leukocyte number and neutrophil number in peripheral

Calcium metabolism in premenopausal women treated by a Gn-RH agonist for uterine myoma.

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Eleven premenopausal women with uterine myoma who received 300 micrograms of intranasal Gn-RH agonist (buserelin) three times daily for 6 months participated in this study. Serum estradiol, some parameters related to calcium metabolism and bone mineral density of the lumbar vertebrae assessed by

The occurrence of human placental alkaline phosphatase (PLAP) in extracts of normal, benign and malignant tissues of the female genital tract.

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In addition to its presence in extracts of carcinomatous tissues from the vulva, endometrium and ovary, PLAP can also be found in tissue extracts of benign conditions of the endometrium and myometrium. We detected slightly elevated levels of PLAP in patients with myoma, raised levels in 2/2 patients

Acid phosphatase of neutrophils in patients with malignancies.

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In 132 patients suffering from various malignancies, including uterine carcinoma, breast cancer, gastric carcinoma, cancer of the colon, and additionally, patients with uterine myomas and endometriosis an increased activity of AP within the peripheral blood neutrophils could be stated by using a

Bone mineral density after concurrent chemoradiation in patients with uterine cervical cancer.

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OBJECTIVE The aim of this study was to examine the bone mineral density (BMD) of women with cervical cancer treated with chemoradiation and to compare the outcomes with those of women with myomas treated by hysterectomy. METHODS The BMDs of 43 women with cervical cancer treated with concurrent

PTEN expression in patients with carcinoma of the cervix and its association with p53, Ki-67 and CD31.

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OBJECTIVE To investigate protein expression and mutations in phosphatase and tensin homolog (PTEN) in patients with stage IB cervical squamous cell carcinoma (CSCC) and the association with clinical-pathologic features, tumor p53 expression, cell proliferation and angiogenesis. METHODS Women with

Experience with leuprorelin acetate depot in the treatment of fibroids: a German multicentre study.

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Between October 1988 and October 1990 in a noncomparative multicentre study, 114 patients were treated for uterine fibroids with the gonadotrophin-releasing hormone (Gn-RH) agonist, leuprorelin acetate depot. The mean age of the women was 33 years and 55.3% of them had a history of infertility.

[Tissue repair of uterine cervix--cell-biological properties of normal uterine cervical epithelia of transformation zone in vitro].

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The objective of this study is to culture the epithelia of the transformation zone of the uterine cervix for long term and evaluate their biological characteristics, such as morphology, growth behavior, alkaline phosphatase activity and heterotransplantability. The epithelia of transformation zone

[Enzyme activity in the blood serum and lymphocytes of patients with chronic salpingo-oophoritis combined with benign tumors of the genitalia].

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The activity of some enzymes was examined in blood serum and lymphocytes of women with chronic salpingo-oophoritis in combination with tumourous processes of the genital organs. The objects of the study were 96 women, divided into three groups: first group (control)-20 healthy women, second group-37

[The effects of progestin on the bone metabolism in postmenopausal women].

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Thirty postmenopausal women, including 26 with history of hysterectomy and bilateral salpingooophorectomy due to uterine myoma and 4 with natural menopause without any diseases were randomly allocated into two groups. Fifteen subjects received medroxyprogesterone acetate (MPA) 10 mg twice daily for

Endometrial immunocompetent cells in proliferative and secretory phase of normal menstrual cycle.

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Menstruation was presented as a result of inflammatory process. The total and relative numbers of the endometrial immunocompetitive cells vary during the different phases of the menstrual cycle. The aim of this morphological study is to make a contribution in understanding different

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