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myoma/proline

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The concentrations of collagen-associated amino acids are higher in GnRH agonist-treated uterine myomas.

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OBJECTIVE To test the hypothesis that the effects of estrogen reduction on uterine leiomyoma regression are mediated through changes in cell density or the extracellular matrix. METHODS Uterine myomas were obtained from 20 women who had received randomly either the GnRH agonist leuprolide acetate

[Histological and biochemical studies of collagen in human uterine leiomyomas].

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Forty eight human uteri including normal group (16 cases), adenomyosis group (5 cases) and myoma group (27 cases) were studied to clarify the pathogenesis of uterine leiomyomas on the viewpoint of the collagen metabolism. The leiomyomas in the myoma group were histologically divided into the three
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