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oropharyngeal neoplasms/mučnina

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ČlanciKliničkim ispitivanjimaPatenti
Page 1 od 19 rezultati
UNASSIGNED To correlate the planned dose to the nausea center (NC) - area postrema (AP) and dorsal vagal complex (DVC) - with nausea and vomiting symptoms in OPC patients treated with IMRT without chemotherapy. We also investigated whether it was possible to reduce doses to the NC without
Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatment-related toxicity. Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and
Intensity-modulated radiation therapy (IMRT) is becoming the treatment of choice for many head and neck cancer patients. IMRT reduces some toxicities by reducing radiation dose to uninvolved normal tissue near tumor targets; however, other tissues not irradiated using previous 3D techniques may
OBJECTIVE Nausea and vomiting have been known to occur in patients undergoing external beam radiation treatments for head&neck cancers. We sought to determine the feasibility of limiting the dose delivered to the nausea center, area postrema (AP) and dorsal vagal complex (DVC), for these patients

Reduced radiation-induced toxicity by using proton therapy for the treatment of oropharyngeal cancer.

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Patients with squamous cell carcinoma of the oropharynx are generally treated with (chemo) radiation. Patients with oropharyngeal cancer (OPC) have better survival than patients with squamous cell carcinoma of other head and neck subsites, especially when related to human papillomavirus (HPV).
A potential advantage of intensity-modulated proton therapy (IMPT) over intensity-modulated (photon) radiation therapy (IMRT) in the treatment of oropharyngeal carcinoma (OPC) is lower radiation dose to several critical structures involved in the development of nausea and vomiting, mucositis, and
OBJECTIVE Prognosis in patients with recurrent or metastatic squamous cell carcinoma of the head and neck is poor, and systemic chemotherapy has an only modest impact on the outcome. Chemotherapy with cisplatin plus 5-FU (PF) is widely used, but the standard dosage, PF (100/1000; cisplatin 100

Tube feeding during treatment for head and neck cancer - Adherence and patient reported barriers.

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The main aim was to investigate the incidence of patient adherence to nutritional tube feeding recommendations in patients with head and neck cancer and to determine patient barriers to meeting tube feeding prescription. This was an observational study from a randomised controlled trial in patients

Cervical pharyngostomy: an alternative approach to enteral feeding.

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Surgical patients may be unable or unwilling to feed normally, owing to mechanical obstruction to ingestion because of nausea or anorexia or secondary to neurologic abnormality. Such patients may be in a malnourished state that compromises their chances of successful recovery. The Nasogastric tube

A pilot study of the efficacy of varenicline for the treatment of smokeless tobacco users in Midwestern United States.

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BACKGROUND Long-term smokeless tobacco (ST) use is known to increase the risk for oropharyngeal cancer, heart attack, and stroke. Varenicline has recently been demonstrated to increase ST abstinence rates among Swedish snus users. We have conducted a pilot study to obtain preliminary evidence of

A pilot study to assess smokeless tobacco use reduction with varenicline.

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BACKGROUND Long-term smokeless tobacco (ST) use is known to increase the risk for oropharyngeal cancer, heart attack, and stroke. Extant literature on cigarette smokers suggests that smoking reduction increases smoking abstinence among smokers not interested in quitting. Similarly, a reduction

Feasibility of photofrin II as a radiosensitizing agent in solid tumors--preliminary results.

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BACKGROUND Photofrin II has been demonstrated to serve as a specific and selective radiosensitizing agent in in vitro and in vivo tumor models. We aimed to investigate the feasibility of a clinical application of Photofrin II. METHODS 12 patients were included in the study (7 unresectable solid

[Fibrous hemangioma of esophagus portal: a case report].

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A 33 year old male patient has found in the oral cavity tumor with nausea and vomiting after 20 days ago. The patients feel pharyngeal foreign body sensation, occasional sense of suffocation, the oropharyngeal tumor disappeared and foreign body sensation disappeared after swallowing. The patients
OBJECTIVE A phase II study was conducted to test the efficacy and toxicity of the combination of cisplatin, 5-Fu and nimotuzumab, as induction treatment of resectable head and neck squamous cell carcinoma (HNSCC). METHODS Forty cases of resectable HNSCC were treated with nimotuzumab (400 mg on day
Purpose: Preclinical models have shown that the effectiveness of GL-ONC1, a modified oncolytic vaccinia virus, is enhanced by radiation and chemotherapy. The purpose of this study was to determine the safety of GL-ONC1 when delivered intravenously with chemoradiotherapy to patients with primary,
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