orthostatic intolerance/edema

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Vascular perturbations in the chronic orthostatic intolerance of the postural orthostatic tachycardia syndrome.

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Chronic orthostatic intolerance is often related to the postural orthostatic tachycardia syndrome (POTS). POTS is characterized by upright tachycardia. Understanding of its pathophysiology remains incomplete, but edema and acrocyanosis of the lower extremities occur frequently. To determine how

Pooling in chronic orthostatic intolerance: arterial vasoconstrictive but not venous compliance defects.

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BACKGROUND Orthostatic intolerance is characterized by postural tachycardia syndrome (POTS) with exaggerated tachycardia, orthostatic symptoms, and "pooling" (which comprises acrocyanosis and dependent edema when upright). My colleagues and I tested the hypothesis that pooling results from increased

Active compression garment prevents tilt-induced orthostatic tachycardia in humans.

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Compression garments are used by patients with lower extremity edema to help regulate fluid distribution and to prevent orthostatic symptoms. Current compression stockings are often reported as uncomfortable and adherence is poor. The current study was conducted to assess the efficacy of a novel

Effects of acute hypoxia on cardiopulmonary responses to head-down tilt.

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Six male subjects were exposed on two separate occasions to simulated microgravity with 28 degrees head-down tilt (HD) for 1 h with baseline followed by recovery at + 17 degrees head-up. Pulmonary ventilation, gas exchange, spirometry, and central and cerebral blood flow characteristics were

Calf blood flow during prolonged tilt in idiopathic dilated cardiomyopathy and after cardiac transplantation.

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In severe congestive heart failure (CHF), abnormal reflex control of calf blood flow during brief head-up tilt that appears to normalize after transplantation (HTX) may be present during prolonged observation also. Therefore, we studied the effect of prolonged (30 min) 50 degrees head-up tilt on

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