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6 rezultati
Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats.
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Osthole, a natural coumarin derivative, has taken considerable attention because of its diverse pharmacological functions. It has been reported to be useful in the treatment of chronic cerebral hypoperfusion and neuronal damage. In the present study, we examined the neuroprotective effect of osthole
Neuroprotective effects of osthole pretreatment against traumatic brain injury in rats.
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Osthole, a coumarin compound isolated from the plant-derived herb Cnidium monnieri, has been the subject of considerable interest because of its broad spectrum of pharmacological properties. The aim of this study was to investigate the potential protective effects of osthole in adult rats in the
Anti-inflammatory effect and mechanism of osthole in rats.
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OBJECTIVE
To investigate the anti-inflammatory effect and mechanism of osthole (Ost).
METHODS
Carrageenan -induced hind paw edema in rats were prepared. The nitric oxide synthase (NOS) activity was measured by NADPH -diaphoras stain assay, nitric oxide (NO) content by Griess diazotization assay,
Anti-inflammatory and analgesic activities from roots of Angelica pubescens.
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In the present study, we extracted Angelica pubescens (AP) with various solvents in order to find the bioactive constituents that demonstrated analgesic and anti-inflammatory effects. The results were obtained as follows: (1) Methanol-, chloroform-, and ethyl acetate-extracts effectively reduced the
Inhibition of the Warm Temperature-Activated Ca2+-Permeable Transient Receptor Potential Vanilloid TRPV3 Channel Attenuates Atopic Dermatitis.
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Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by cutaneous lesions and intense pruritus. The warm temperature-activated Ca2+-permeable transient receptor potential vanilloid (TRPV)3 channel is abundantly expressed in keratinocytes, and gain-of-function
Anti-inflammatory and antinociceptive activity of coumarins from Seseli gummiferum subsp. corymbosum (Apiaceae).
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n-Hexane and ethyl acetate extracts as well as coumarin derivatives obtained from the n-hexane extract of the aerial parts of Seseli gummiferum Pall. ex Sm. subsp. corymbosum (Boiss. & Heldr.) P.H. Davis (Apiaceae) were evaluated in vivo for their anti-inflammatory and antinociceptive activities.
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