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perillyl alcohol/hipersenzitivnost

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Perillyl alcohol suppresses antigen-induced immune responses in the lung.

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Perillyl alcohol (POH) is an isoprenoid which inhibits farnesyl transferase and geranylgeranyl transferase, key enzymes that induce conformational and functional changes in small G proteins to conduct signal production for cell proliferation. Thus, it has been tried for the treatment of cancers.

Oral monoterpene therapy (perillyl alcohol) reduces vein graft intimal hyperplasia.

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The development of intimal hyperplasia is recognized as a major impediment to graft patency. D-Limonenes are monoterpenes with a recognized cytostatic effect on cell proliferation by inhibiting posttranslational isoprenylation of p21ras and other small G-proteins. This study examines the effect of

Anticandidal Effect and Mechanisms of Monoterpenoid, Perillyl Alcohol against Candida albicans.

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This study explored the antifungal potential of perillyl alcohol (PA), a natural monoterpene alcohol, against most prevalent human fungal pathogen C. albicans, its clinical isolates and four non-albicans species of Candida. To resolve the potential mechanisms, we used whole genome transcriptome

Effect of D-limonene on immune response in BALB/c mice with lymphoma.

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The monoterpene D-limonene and its metabolites have been shown to exert chemopreventive and chemotherapeutic activities against different tumors in animal models and clinical trials. However, it is unknown whether these compounds modulate the immune response in tumor-bearing mice. We evaluated the
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