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polyalthic acid/copaifera officinalis

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Synthesis and biological evaluation of polyalthic acid derivatives for the treatment of neglected diseases.

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Polyalthic acid is a naturally occurring diterpene found in copaiba oil, one of the most popular natural medicines in the Amazon. Based on the reported antileishmanial activity of copaiba oil, a series of amides and diols derivatives of polyalthic acid were synthesized and tested against Leishmania

Biological Activities of Two Major Copaiba Diterpenoids and Their Semi-synthetic Derivatives

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The oleoresin of Copaifera reticulata Ducke, Fabaceae, is a traditional Brazilian remedy used for a wide range of applications. Commonly named copaiba, the oleoresin has been found to exhibit strong antimicrobial effects in our previous study, which could be attributed to some of its

Chemopreventive role of Copaifera reticulata Ducke oleoresin in colon carcinogenesis.

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In Brazilian folk medicine, copaiba oleoresin is widely known for its therapeutic activity, especially its wound healing and anti-inflammatory actions. Considering the relationship between inflammatory processes and carcinogenesis, this paper reports on the Copaifera reticulata Ducke oleoresin (CRO)

Antimicrobial and cytotoxic effects of the Copaifera reticulata oleoresin and its main diterpene acids.

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BACKGROUND The oleoresin of Copaifera reticulata is a traditional Brazilian remedy used for the treatment of skin and urinary tract infections, respiratory diseases, rheumatism, ulcer and tumours; thus, playing an important role in the primary health care of the indigenous population. OBJECTIVE As

Copaifera of the Neotropics: A Review of the Phytochemistry and Pharmacology.

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The oleoresin of Copaifera trees has been widely used as a traditional medicine in Neotropical regions for thousands of years and remains a popular treatment for a variety of ailments. The copaiba resins are generally composed of a volatile oil made up largely of sesquiterpene hydrocarbons, such as
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