This is a single arm study comparing changes within patients before and after receiving the experimental drug Polyphenon E for the duration of the study, between recruitment and surgery for breast cancer.

Single arm for a phase II study of EGCG extract and breast cancer. Subjects are asked to take 4 polyphenol E (200mg) capsules daily with a meal for the duration of the study. Biomarkers are measured at baseline and then again at presurgery, the end point for the study.

ECGC and Breast Cancer

Sex: Female, Male

Region of Enrollment

Change in serum VEGF from baseline to post treatment with polyphenon E.

Change in Serum VEGF in Breast Cancer

Change in serum HGF from baseline to post Polyphenol E treatment.

The effect of ECGC extract on biomarkers in breast cancer.

Change in Serum HGF and Breast Cancer

Overall Study

Dr. Jerry w. McLarty, Ph.D.

Breast Cancer

Four 200mg capsules daily taken with a meal, for the duration of the study.

Polyphenon E

LSU Health Sciences Center

Columbia Presbyterian Hospital

A Study of the Effect of Polyphenon E (Green Tea Extract) on Breast Cancer Progression

Phase II Clinical Trial to Determine if Polyphenon E Inhibits c-Met Signaling and Activation of Pathways Contributing to Breast Cancer Progression

Jerry McLarty

Professor

Louisiana State University Health Sciences Center Shreveport

Columbia University

Breast Neoplasms

Mastectomy

Solu-medrol 125 mg

Herlev Hospital, breast surgery

Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma

Herlev Hospital

proteinase

tumori dojke

breast neoplasms

proteinase/tumori dojke

A Study of the Effect of Polyphenon E (Green Tea Extract) on Breast Cancer Progression

Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma

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