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3 rezultati
Comparative Evaluation of the Antioxidant and Anti-Alzheimer's Disease Potential of Coumestrol and Puerarol Isolated from Pueraria lobata Using Molecular Modeling Studies.
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The current study assesses the antioxidant effects of two similar isoflavonoids isolated from Pueraria lobata, coumestrol and puerarol, along with the cholinergic and amyloid-cascade pathways to mitigate Alzheimer's disease (AD). Antioxidant activity was evaluated via 1,1-diphenyl-2-picryhydrazyl
[Chemical constituents from roots of Pueraria lobata].
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OBJECTIVE
To study the chemical constituents in the roots of Pueraria lobata.
METHODS
Various chromatographic methods were employed to separate of chemical constituents and the spectroscopic methods were used to elucidate the structure.
RESULTS
Twenty-two compounds were isolated and characterized as
Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots.
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In order to evaluate the anti-inflammatory and antioxidant activities of Pueraria lobata roots and its active components, in vitro inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) protein
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