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Page 1 od 65 rezultati
CDNA encoding the human .alpha.2 .delta.4 calcium channel subunit
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Voltage gated calcium channels (VGCC) mediate Ca.sup.2+ entry into cells in response to membrane depolarization (Catterall, W. A.(1988) Science 242:50-61 and Bean B P. (1989) Annu. Rev. Physiol. 51:367-368). Ca.sup.2+ entering the cell through voltage-gated Ca.sup.2+ channels serves as the second
Aryl-link-aryl substituted thiazolidine-dione and oxazolidine-dione as sodium channel blockers
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BACKGROUND OF THE INVNON
1. Field of the Invention
The present invention is directed to aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds. In particular, this invention is directed to aryl-link-aryl thiazohdine-ione, and aryl-link-aryl oxazolidine-dione compounds which
Substituted 2,3-benzodiazepin-4-ones and the use thereof
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This application claims benefit of U.S. provisional application Ser. No. 60/013,813 filed Mar. 21, 1996.
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is in the field of medicinal chemistry. In particular, the invention relates to novel substituted 2,3-benzodiazepin-4-ones.
L-DOPA ethyl ester salts and uses thereof
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Throughout this application, various references are cited, using arabic numbers within parentheses. Full citations for these references can be found at the end of the specification, immediately preceding the claims. These publications, in their entireties, are hereby incorporated by reference into
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Piperazine Compounds, compositions comprising a Piperazine Compound and methods for treating or preventing a condition such as pain, urinary incontinence (UI), an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy,
Therapeutic agents useful for treating pain
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REFERENCE TO SEQUENCE LISTING SUBMITTED ELECTRONICALLY
The content of the electronically submitted Sequence Listing (Name: sequence_listing_ascii.txt; Size: 766 bytes; and Date of Creation: Mar. 19, 2012) filed herewith is incorporated herein by reference in its entirety.
1. FIELD OF THE
2-pyridinyl-1-piperazine therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Piperazine Compounds; compositions comprising a Piperazine Compound; and methods for preventing or treating pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an addictive disorder,
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Cycloheteroalkenyl Compounds, compositions comprising an effective amount of a Cycloheteroalkenyl Compound and methods for treating or preventing a condition such as pain comprising administering to an animal in need thereof an effective
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Piperazine Compounds; compositions comprising a Piperazine Compound; and methods for preventing or treating pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an addictive disorder,
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Benzoazolylpiperazine Compounds, compositions comprising a Benzoazolylpiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Benzoazolylpiperazine Compounds, compositions comprising a Benzoazolylpiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Benzoazolylpiperazine Compounds, compositions comprising a Benzoazolylpiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Benzoazolylpiperazine Compounds, compositions comprising a Benzoazolylpiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Benzoazolylpiperazine Compounds, compositions comprising a Benzoazolylpiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Cyanoiminopiperazine Compounds, compositions comprising an effective amount of a Cyanoiminopiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD),
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