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securinine/phyllanthus
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Antifungal Activity of Nor-securinine Against Some Phytopathogenic Fungi.
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Crude extracts and active principles from medicinal plants have shown potential role in controlling plant diseases in glasshouses as well as in fields as one of the safest and ecofriendly methods. The effect of nor-securinine (an alkaloid) isolated from Phyllanthus amarus has been seen against spore
4-Methoxy-nor-Securinine, a New Alkaloid from Phyllanthus niruri.
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From the aerial parts of PHYLLANTHUS NIRURI L. (Euphorbiaceae) plant two alkaloids 4-methoxy-securinine (phyllanthine) ( 1) and 4-methoxy-nor-securinine ( 2) have been isolated and their structures elucidated on the basis of spectroscopic data. The former alkaloid is isolated for the first time from
Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells.
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BACKGROUND
The Securinega-type alkaloids occur in plants belonging to Euphorbiaceae family. One of the most widely distributed alkaloid of this group is securinine, which was identified next to allosecurinine in Phyllanthus glaucus (leafflower). Recently, some Securinega-type alkaloids have paid
[Pharmacodynamics of securinine, present in Phyllanthus discoïdes-Euphorbiaceae].
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Antibacterial activity of the leaves of Phyllanthus discoideus.
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The lyophilized aqueous extract (LWE) from the leaves of Phyllanthus discoideus was found to show an antibacterial activity. The alkaloid fraction obtained from LWE inhibited the growth of Escherichia coli and Enterococcus faecium (MIC = 1.6 mg/ml), Pseudomonas aeruginosa (MIC = 0.78 mg/ml),
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