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Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia

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Taxane Related Arthralgia-Myalgia Syndrome: Paclitaxel and docetaxel are the major representatives of the drug class of taxanes, agents commonly used in the treatment of a variety of solid tumors. They interfere with the mitotic process of dividing cells by stabilizing the microtubules and are the

Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction

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OBJECTIVES: Primary - Determine the feasibility of conducting a randomized placebo-controlled clinical trial for cognitive symptoms in female breast cancer survivors. Secondary - Estimate the variability of the clinical outcomes (FACT-Cognition Perceived Cognitive Impairment subscale, neurocognitive

Cognitive-Behavioral Therapy for Sleep Disturbance in Patients Undergoing Hemodialysis

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Sleep disturbance is common in patients with renal disease. According to previous studies, it occurs in more than 50% of chronic kidney disease (CKD) patients and those undergoing dialysis. 1, 2 Insomnia, restless legs syndrome (RLS), daytime sleepiness, and sleep apnea syndrome are common

Molecular Signature of Valproic Acid in Breast Cancer With Functional Imaging Assessment - a Pilot

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Before treatment each woman needs a DCE-MRI and a biopsy of the breast mass. For women who have had diagnoses of breast cancer outside our institution, the study procedures are illustrated in figure 1. Following screening labs and enrollment, a DCE-MRI will be performed followed by a biopsy to

Does Postoperative Gabapentin Reduce Pain, Opioid Consumption and Anxiety and Have a Positive Effect on Health Related Quality of Life After Radical Prostatectomy?

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Gabapentin Gabapentin is an anti-epileptic agent originally developed to treat spasticity (1), and eventually was found to be effective against chronic neuropathic pain (1,2). Gabapentin is available as an oral preparation and is primarily absorbed in the small intestine (1). Gabapentin is not

Sleep, Circadian Hormonal Dysregulation, and Breast Cancer Survival

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