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spondylitis/phosphatase

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Increased serum alkaline phosphatase activity in ankylosing spondylitis.

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Raised serum alkaline phosphatase (AP) levels were found in 13 of 76 patients (17%) with ankylosing spondylitis (AS), and 11 of these 13 underwent further investigation to determine the origin of the increased enzyme activity. Three had levels within the normal reference range on re-estimation, and,
BACKGROUND Ankylosing spondylitis (AS) is a chronic autoimmune disease that involves the imbalance of peripheral tolerance possibly caused by the negative signal of activated T cells. The polymorphisms in the human protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene have been pointed out
OBJECTIVE Although ankylosing spondylitis (AS) is driven by immune-mediated processes, little is known about the presence and role of autoantibodies in this disease. This study was undertaken to investigate whether autoantibodies occur in and are involved in AS. METHODS We performed human protein

Regulation of osteoblasts by alkaline phosphatase in ankylosing spondylitis.

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OBJECTIVE Ankylosing spondylitis (AS) is characterized by excessive spinal ankylosis and bone formation. Alkaline phosphatase (ALP) activity is reported to be high in AS, but little is known about the molecular relationship between ALP and AS. The aims of this study were to investigate the relevance

HLA-B27-mediated activation of TNAP phosphatase promotes pathogenic syndesmophyte formation in ankylosing spondylitis.

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Ankylosing spondylitis (AS) is a type of axial inflammation. Over time, some patients develop spinal ankylosis and permanent disability; however, current treatment strategies cannot arrest syndesmophyte formation completely. Here, we used mesenchymal stem cells (MSCs) from AS patients (AS MSCs)

[Calcium and phosphorus levels and phosphatase activity in the blood of patients with a ankylosing spondylitis].

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[Effect of sulfur water baths on phosphatases in ankylosing spondylitis].

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Serum alkaline phosphatase in ankylosing spondylitis.

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The phosphatase activity in spondylitis ankylopoietica.

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The Phosphatase Activity in Spondylitis Ankylopoietica.

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Serum leptin levels are associated with the presence of syndesmophytes in male patients with ankylosing spondylitis.

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The aim of this study is to clarify the association between serum leptin levels and the presence of syndesmophytes in male patients with ankylosing spondylitis (AS). Seventy-two male patients with AS and 20 age-matched healthy male controls were included. Patients were stratified by the presence of
BACKGROUND Purpose of the study was: 1) to assess the best localization and the method for diagnosis of osteoporosis; 2) to assess risk factors of osteoporosis; 3) to assess risk factors of spinal fractures due to osteoporosis; 4) assessment of bone metabolism. METHODS The study consisted of 46 male

Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl.

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Vitamin D-deficient rickets (VDDR) remains an important health problem especially in developing countries. Insufficient dietary intake of vitamin D and inadequate sun exposure increase the risk of vitamin D deficiency. Since their vitamin D requirement is increased, children and adolescents are

Hepatic function in ankylosing spondylitis.

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Values for alkaline phosphatase and gamma glutamyl transpeptidase (GGTP) and the prevalence of their elevation was significantly higher in 35 patients with ankylosing spondylitis (AS) than in 35 age and sex matched controls. The abnormal enzyme levels appeared to reflect a non-specific reaction to
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