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steroid saponin/nekroza
Veza se sprema u međuspremnik
3 rezultati
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.
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The aim of the study was to investigate the protective effect of dioscin against APAP-induced hepatotoxicity. In the in vitro tests, HepG2 cells were given APAP pretreatment with or without dioscin. In the in vivo experiments, mice were orally administrated dioscin for five days and then given APAP.
Dioscin alleviates lipopolysaccharide-induced acute lung injury through suppression of TLR4 signaling pathways.
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Aim:Acute lung injury (ALI) is a life-threatening inflammatory syndrome that lacks an effective therapy. Dioscin, a natural steroid saponin isolated from a variety of herbs, could serve as an anti-inflammatory agent, as suggested in previous reports. The purpose of this study was to explore
Dioscin Promotes Proliferation of Pancreatic Beta Cells via Wnt/β-Catenin Signaling Pathways.
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BACKGROUND
Dysfunction of pancreatic beta cells is related with type 2 diabetes mellitus. Dioscin, a natural steroid saponin, has many pharmacological effects. The aim of this study was to investigate the effects of dioscin on apoptosis of pancreatic beta cells induced by high
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